Academic Journal
Negative regulation of violacein biosynthesis in Chromobacterium violaceum
| العنوان: | Negative regulation of violacein biosynthesis in Chromobacterium violaceum |
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| المؤلفون: | Devescovi, Giulia, Kojic, Milan, Covaceuszach, Sonia, C�mara, Miguel, Williams, Paul, Bertani, Iris, Subramoni, Sujatha, Venturi, Vittorio |
| بيانات النشر: | Frontiers Media |
| سنة النشر: | 2017 |
| المجموعة: | University of Nottingham: Repository@Nottingham |
| مصطلحات موضوعية: | Chromobacterium violaceum, VioS, CviI/R quorum sensing, regulation, Violacein, Chitinase activity, Protease activity |
| الوصف: | In Chromobacteium violaceum, the purple pigment violacein is under positive regulation by the N-acylhomoserine lactone CviI/R quorum sensing system and negative regulation by an uncharacterized putative repressor. In this study we report that the biosynthesis of violacein is negatively controlled by a novel repressor protein, VioS. The violacein operon is regulated negatively by VioS and positively by the CviI/R system in both C. violaceum and in a heterologous Escherichia coli genetic background. VioS does not regulate the CviI/R system and apart from violacein, VioS and quorum sensing regulate other phenotypes antagonistically. Quorum sensing regulated phenotypes in C. violaceum are therefore further regulated providing an additional level of control. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | https://nottingham-repository.worktribe.com/output/845155; Frontiers in Microbiology; Volume 8 |
| DOI: | 10.3389/fmicb.2017.00349 |
| الاتاحة: | https://doi.org/10.3389/fmicb.2017.00349 https://nottingham-repository.worktribe.com/file/845155/1/251601_Venturi_Manuscript.pdf https://nottingham-repository.worktribe.com/output/845155 |
| Rights: | openAccess |
| رقم الانضمام: | edsbas.4D98A816 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3389/fmicb.2017.00349 |
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