Academic Journal
PET measurements of myocardial glucose metabolism with 1-11C-glucose and kinetic modeling
| العنوان: | PET measurements of myocardial glucose metabolism with 1-11C-glucose and kinetic modeling |
|---|---|
| المؤلفون: | Pilar Herrero, Zulfia Kisrieva-ware, Carmen S. Dence, Bruce Patterson, Andrew R. Coggan, Dong-ho Han, Yosuke Ishii, Paul Eisenbeis, Robert J. Gropler |
| المساهمون: | The Pennsylvania State University CiteSeerX Archives |
| المصدر: | http://jnm.snmjournals.org/content/48/6/955.full.pdf. |
| سنة النشر: | 2007 |
| المجموعة: | CiteSeerX |
| الوصف: | The aim of this study was to investigate whether compartmental modeling of 1-11C-glucose PET kinetics can be used for noninva-sive measurements of myocardial glucose metabolism beyond its initial extraction. Methods: 1-11C-Glucose and U-13C-glucose were injected simultaneously into 22 mongrel dogs under a wide range of metabolic states; this was followed by 1 h of PET data acquisition. Heart tissue samples were analyzed for 13C-glycogen content (nmol/g). Arterial and coronary sinus blood samples (ART/CS) were analyzed for glucose (mmol/mL), 11C-glucose, 11CO2, and 11C-total acidic metabolites (11C-lactate [LA] 1 11CO2) (counts/min/mL) and were used to calcu-late myocardial fractions of (a) glucose and 1-11C-glucose |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.520.9997; http://jnm.snmjournals.org/content/48/6/955.full.pdf |
| الاتاحة: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.520.9997 http://jnm.snmjournals.org/content/48/6/955.full.pdf |
| Rights: | Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: | edsbas.4D44AD44 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |