التفاصيل البيبلوغرافية
| العنوان: |
Regulation of SOCS-1 and ISGs expression is independent of the MOI used. |
| المؤلفون: |
Jorge Andrés Castillo (11547632), Diana M. Giraldo (11547635), Juan C. Hernandez (9365387), Jolanda M. Smit (9220676), Izabela A. Rodenhuis-Zybert (7592744), Silvio Urcuqui-Inchima (355826) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Ecology, Immunology, Developmental Biology, Mental Health, Infectious Diseases, Plant Biology, Virology, reactive oxygen species, protein kinase r, promising therapeutics mitigating, important cellular targets, ifn -&# 945, borne dengue virus, severe disease caused, restrict virus replication, produce lower levels, innate immune responses, div >< p, although vitd3 treatment, exacerbated inflammatory response, inflammatory cytokines, higher levels, viral replication, taken together, results suggest, reduced infection |
| الوصف: |
The MDMs were differentiated in the presence of VitD3 (0.1 nM) for 6 days (D 3 -MDMs) and then infected with DENV-2 with different MOIs for 24 h. Expression of SOCS-1 (A and D), PKR (B and E), and OAS1 (C and F) were measured by qPCR in MDMs and D 3 -MDMs using ubiquitin as a housekeeper. Data are expressed as fold change relative to mock-treated MDMs and D 3 -MDMs. Three different donors were analyzed. Differences were obtained with a two-way ANOVA with a Bonferroni posthoc test and a 95% confidence interval (***p < 0.001, **p < 0.01, *p < 0.05). |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/figure/Regulation_of_SOCS-1_and_ISGs_expression_is_independent_of_the_MOI_used_/16785494 |
| DOI: |
10.1371/journal.pntd.0009873.g006 |
| الاتاحة: |
https://doi.org/10.1371/journal.pntd.0009873.g006 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.4CDEBBB |
| قاعدة البيانات: |
BASE |