Academic Journal
Methyl 8- and 5-Nitro-1,4-Benzodioxane-2-Carboxylate
| العنوان: | Methyl 8- and 5-Nitro-1,4-Benzodioxane-2-Carboxylate |
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| المؤلفون: | E. Armano, A. Giraudo, C. Morano, M. Pallavicini, C. Bolchi |
| المساهمون: | E. Armano, A. Giraudo, C. Morano, M. Pallavicini, C. Bolchi |
| بيانات النشر: | MDPI |
| سنة النشر: | 2023 |
| المجموعة: | The University of Milan: Archivio Istituzionale della Ricerca (AIR) |
| مصطلحات موضوعية: | 8-nitro-1,4-benzodioxane-2-carboxylate, 5-nitro-1,4-benzodioxane-2-carboxylate, HMBC NMR, regioisomer, structure elucidation, Settore CHIM/08 - Chimica Farmaceutica |
| الوصف: | 2-Substituted 1,4-benzodioxanes bearing one or more substituents at benzene are important templates in the design and synthesis of a large variety of biologically active compounds. One of the most straightforward synthetic strategies to prepare them in racemic form and with a 2-substituent susceptible to further synthetically useful conversions is the condensation of commercially available methyl 2,3-dibromopropionate with already suitably functionalized catechol. Here, we obtain methyl 8- and 5-nitro-1,4-benzodioxane-2-carboxylate by reaction of methyl 2,3-dibromopropionate with 3-nitrocatechol. After separation, the two positional isomers could be unequivocally identified by HMBC NMR analysis. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/wos/WOS:001015270700001; volume:2023; issue:2; firstpage:1; lastpage:7; numberofpages:7; journal:MOLBANK; https://hdl.handle.net/2434/984488; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85163791270 |
| DOI: | 10.3390/M1661 |
| الاتاحة: | https://hdl.handle.net/2434/984488 https://doi.org/10.3390/M1661 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.4CA482C4 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/M1661 |
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