Academic Journal
Fabrication, Mercury Intrusion Porosimetry Characterization and In Vitro Qualitative Analysis of Biocompatibility of Various Porosities Polycaprolactone Scaffolds
| العنوان: | Fabrication, Mercury Intrusion Porosimetry Characterization and In Vitro Qualitative Analysis of Biocompatibility of Various Porosities Polycaprolactone Scaffolds |
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| المؤلفون: | Limongi Tania, Giugni Andrea, Hua Tan, Ebtihaj M Bukhari, Bruno Torre, Marco Allione, Monica Marini, Luca Tirinato, Gobind Das, Manola Moretti, Andrea Falqui, Enzo di Fabrizio |
| المساهمون: | Limongi, Tania, Giugni, Andrea, Hua, Tan, Ebtihaj, M Bukhari, Torre, Bruno, Marco, Allione, Marini, Monica, Luca, Tirinato, Gobind, Da, Manola, Moretti, Andrea, Falqui, DI FABRIZIO, ENZO MARIO |
| بيانات النشر: | Omics |
| سنة النشر: | 2015 |
| المجموعة: | PORTO@iris (Publications Open Repository TOrino - Politecnico di Torino) |
| مصطلحات موضوعية: | biocompatibility, porous scaffolds, fibroblasts |
| الوصف: | In order to develop surfaces with improved cell culture biocompatibility, we optimized a solvent-casting and particulate-leaching fabrication technique to create porous three-dimensional polycaprolactone scaffolds. These biocompatible porous surfaces were realized by means of NaCl particles as porogen; salt leaching by immersion in distilled water created porosity and pore interconnectivity in the material. Scanning electron microscopy and mercury intrusion porosimetry were used for the measurement of porosity, pore size distribution, permeability and compressibility. To evaluate scaffold biocompatibility, fibroblasts were cultured on the porous surfaces and confocal immunofluorescence characterization indicated that they were effective for in vitro cell culture and practical tissue engineering applications. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| Relation: | volume:06; issue:03; numberofpages:6; journal:JOURNAL OF TISSUE SCIENCE & ENGINEERING; http://hdl.handle.net/11583/2853064 |
| DOI: | 10.4172/2157-7552.1000159 |
| الاتاحة: | http://hdl.handle.net/11583/2853064 https://doi.org/10.4172/2157-7552.1000159 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.4C814A22 |
| قاعدة البيانات: | BASE |
| DOI: | 10.4172/2157-7552.1000159 |
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