Canine endogenous adrenocorticotrophic hormone preanalytical stability after sample shipping in dry ice or recyclable ice bars

التفاصيل البيبلوغرافية
العنوان: Canine endogenous adrenocorticotrophic hormone preanalytical stability after sample shipping in dry ice or recyclable ice bars
المؤلفون: Álan Gomes Pöppl (10441532), Carolina Castilhos da Silva (10441739), Guilherme Luiz Carvalho de Carvalho (10441742), Rogério Soila (10441745), Priscila Viau Furtado (10441748)
سنة النشر: 2021
المجموعة: Smithsonian Institution: Digital Repository
مصطلحات موضوعية: Agricultural Biotechnology not elsewhere classified, ACTH determination, shipping method, hyperadrenocorticism, hypercortisolism, hypoadrenocorticism
الوصف: Endogenous adrenocorticotrophic hormone (eACTH) measurement is useful in hypercortisolism and hypoadrenocorticism investigation; however, since the hormone is highly unstable, blood samples require proper processing and storage, as well as shipping is often a step limiting since few laboratories offer this assay in Brazil. The aim of this note was to compare overnight dog´s eACTH preanalytical stability when frozen samples were shipped in dry ice (DI), or with recyclable ice bars (RIB). A total of 56 paired samples for eACTH measurement were analyzed. Blood samples were properly handled, plasma aliquots transferred into plastic microtubes, and stored at -80ºC. The fifty-six paired samples were overnight shipped in two thermic isolated boxes with DI or involved by RIB. Despite there was a high correlation between results from both shipping methods (r Spearman = 0.958, P<0.001), the Wilcoxon matched-pairs rank test showed that the shipping method may influence results (P<0.001). However, this difference does not affect results interpretation. By this way, when DI shipping was not possible, RIB shipping may represent a risk to eACTH preanalytical stability.
نوع الوثيقة: dataset
اللغة: unknown
Relation: https://figshare.com/articles/dataset/Canine_endogenous_adrenocorticotrophic_hormone_preanalytical_stability_after_sample_shipping_in_dry_ice_or_recyclable_ice_bars/14305295
DOI: 10.6084/m9.figshare.14305295.v1
الاتاحة: https://doi.org/10.6084/m9.figshare.14305295.v1
Rights: CC BY 4.0
رقم الانضمام: edsbas.4B39BF61
قاعدة البيانات: BASE
الوصف
DOI:10.6084/m9.figshare.14305295.v1