Academic Journal
Evaluation of reference values for phenotypic tests to detect oxacillin resistance in coagulase-negative staphylococci
| العنوان: | Evaluation of reference values for phenotypic tests to detect oxacillin resistance in coagulase-negative staphylococci |
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| المؤلفون: | Pinheiro, Luiza, Mello, Priscila L., Abraão, Ligia M., Corrente, José Eduardo, Cunha, Maria De Lourdes R.S. |
| المساهمون: | Universidade Estadual Paulista (UNESP) |
| سنة النشر: | 2018 |
| المجموعة: | Universidade Estadual Paulista São Paulo: Repositório Institucional UNESP |
| مصطلحات موضوعية: | coagulase-negative staphylococci, oxacillin resistance, reference breakpoints |
| الوصف: | Aim: To evaluate the adequacy of the disc-diffusion test and E-test® compared with detection of mecA for coagulase-negative staphylococci isolated from blood cultures, nasal swabs and wounds. Results: Agreement between all techniques was observed in 65.7% of cases. The greatest discrepancy between mecA/susceptible E-test was observed for non-epidermidis species. A resistance breakpoint ≤19 mm using the oxacillin disc was found to best classify all coagulase-negative staphylococci isolates; Staphylococcus epidermidis, ≤19 mm (oxacillin) and ≤27 mm (cefoxitin); Staphylococcus haemolyticus and Staphylococcus capitis, ≤21 mm (oxacillin) and ≤18 mm (cefoxitin); Staphylococcus warneri, MICs ≥0.75 mg/l. Conclusion: Although no longer recommended by the Clinical Laboratory Standards Institute, we observed some cases in which only the oxacillin disc-diffusion test detected resistance. The discrepancy between phenotypic tests and mecA is probably due to heterogeneity and borderline resistance. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | 565-575 |
| اللغة: | English |
| تدمد: | 1746-0921 1746-0913 |
| Relation: | Future Microbiology; 1,270; http://dx.doi.org/10.2217/fmb-2017-0221; Future Microbiology, v. 13, n. 5, p. 565-575, 2018.; http://hdl.handle.net/11449/176118; 2-s2.0-85044769919 |
| DOI: | 10.2217/fmb-2017-0221 |
| الاتاحة: | http://hdl.handle.net/11449/176118 https://doi.org/10.2217/fmb-2017-0221 |
| Rights: | closedAccess |
| رقم الانضمام: | edsbas.485A40DD |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 17460921 17460913 |
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| DOI: | 10.2217/fmb-2017-0221 |