التفاصيل البيبلوغرافية
| العنوان: |
F8 causes hypophosphorylation in JAK/STAT pathway. |
| المؤلفون: |
Risa Mia Swain, Anahi Sanchez, Denisse A. Gutierrez, Armando Varela-Ramirez, Renato J. Aguilera |
| سنة النشر: |
2023 |
| مصطلحات موضوعية: |
Biochemistry, Cell Biology, Genetics, Neuroscience, Pharmacology, Biotechnology, Cancer, Hematology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, various disease scenarios, low micromolar range, intrinsic apoptotic pathway, estrogen receptor modulating, chembridge diverset library, carbonyl ]- 4, amino ]- 3, 48 h period, cancer cell lines, lymphoma cell line, 2 -[( 3, identify novel anti, cancer agents, cancer activity, cancer activities, novel thiophene, %22">xlink ">, via <, varied uses, thiophenecarboxylate ) |
| الوصف: |
Human Phosphorylation Kinase Array C55 was conducted on the CCRF-CEM cell line and treated with 2X CC 50 (5.78 μM). This assay was used to determine the phosphorylation status of MAPK and JAK-STAT membranes to gauge phosphorylation. Fold changes were determined using densitometry. Hyperphosphorylation was observed in the MAPK membrane versus the JAK-STAT. Hypophosphorylation was displayed in the JAK 1–2 and STAT 2–5. |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/figure/F8_causes_hypophosphorylation_in_JAK_STAT_pathway_/24887558 |
| DOI: |
10.1371/journal.pone.0295441.g007 |
| الاتاحة: |
https://doi.org/10.1371/journal.pone.0295441.g007
https://figshare.com/articles/figure/F8_causes_hypophosphorylation_in_JAK_STAT_pathway_/24887558 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.4819CA7D |
| قاعدة البيانات: |
BASE |