Continuous monitoring of molecular biomarkers in microfluidic devices

التفاصيل البيبلوغرافية
العنوان: Continuous monitoring of molecular biomarkers in microfluidic devices
المؤلفون: A. Idili, H. Montón, M. Medina-Sánchez, B. Ibarlucea, G. Cuniberti, O. G Schmidt, K. W. Plaxco, C. Parolo
المساهمون: Idili, A, Montón, H, Medina-Sánchez, M, Ibarlucea, B, Cuniberti, G, Schmidt, Og, Plaxco, Kw, Parolo, C
بيانات النشر: Academic press
سنة النشر: 2022
المجموعة: Universitá degli Studi di Roma "Tor Vergata": ART - Archivio Istituzionale della Ricerca
مصطلحات موضوعية: Analytical device, Biosensor, Continuous sensing, Diagnostic, Real-time sensing, Settore CHIM/01 - CHIMICA ANALITICA
الوصف: The ability to monitor molecular targets is crucial in fields ranging from healthcare to industrial processing to environmental protection. Devices employing biomolecules to achieve this goal are called biosensors. Over the last half century researchers have developed dozens of different biosensor approaches. In this chapter we analyze recent advances in the biosensing field aiming at adapting these to the problem of continuous molecular monitoring in complex sample streams, and how the merging of these sensors with lab-on-a-chip technologies would be beneficial to both. To do so we discuss (1) the components that comprise a biosensor, (2) the challenges associated with continuous molecular monitoring in complex sample streams, (3) how different sensing strategies deal with (or fail to deal with) these challenges, and (4) the implementation of these technologies into lab-on-a-chip architectures.
نوع الوثيقة: book part
اللغة: English
Relation: info:eu-repo/semantics/altIdentifier/isbn/978-03-23853-03-3; ispartofbook:Progress in molecular biology and translational science; firstpage:295; lastpage:333; numberofpages:39; https://hdl.handle.net/2108/312623; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85113343564; https://www.sciencedirect.com/science/article/abs/pii/S1877117321001678
DOI: 10.1016/bs.pmbts.2021.07.027
الاتاحة: https://hdl.handle.net/2108/312623
https://doi.org/10.1016/bs.pmbts.2021.07.027
https://www.sciencedirect.com/science/article/abs/pii/S1877117321001678
رقم الانضمام: edsbas.47709DAB
قاعدة البيانات: BASE
الوصف
DOI:10.1016/bs.pmbts.2021.07.027