Report
Trans-arterial therapy for Fibrolamellar carcinoma: A case report and literature review
| العنوان: | Trans-arterial therapy for Fibrolamellar carcinoma: A case report and literature review |
|---|---|
| المؤلفون: | Bernon, M. M., Gandhi, Karan, Allam, H., Singh, S., Kloppers, J., Jonas, E. |
| المصدر: | General Surgery, East Africa |
| بيانات النشر: | eCommons@AKU |
| سنة النشر: | 2022 |
| المجموعة: | The Aga Khan University: eCommons@AKU |
| مصطلحات موضوعية: | Fibrolamellar carcinoma Trans-arterial embolization, Trans-arterial chemo-embolization, Trans-arterial radio-embolization, Surgery |
| الوصف: | Introduction: Fibrolamellar carcinoma (FLC) is a rare pathologically distinct primary liver cancer. Surgical resection is the only treatment associated with prolonged survival. Trans-arterial embolization (TAE), which is a recognised treatment for hepatocellular carcinoma has been used to treat FLC. We present a case and performed a literature review of patients with FLC treated with TAE. Case presentation: We present a 19-year old female with a large potentially resectable FLC which was initially treated with trans-arterial chemo-embolization (TACE) with drug eluting beads. The TACE was followed by surgical resection. Histology confirmed tumour necrosis related to the previous TACE. Discussion & literature review: We identified seven case reports and one case series of TAE for FLC. TAE was either used as a neo-adjuvant therapy to facilitate subsequent tumour resection or as a palliative treatment modality. We propose an algorithm for the treatment of FLC that includes TAE. Conclusion: The rarity of FLC and the paucity of data precludes establishing clear evidence-based standards of care. We propose an algorithm for the treatment of FLC. The establishment of an international registry may facilitate the collection of better quality evidence. |
| نوع الوثيقة: | report |
| وصف الملف: | application/pdf |
| اللغة: | unknown |
| Relation: | https://ecommons.aku.edu/eastafrica_fhs_mc_gen_surg/68; https://ecommons.aku.edu/context/eastafrica_fhs_mc_gen_surg/article/1080/viewcontent/1_s2.0_S2210261222002267.pdf |
| الاتاحة: | https://ecommons.aku.edu/eastafrica_fhs_mc_gen_surg/68 https://ecommons.aku.edu/context/eastafrica_fhs_mc_gen_surg/article/1080/viewcontent/1_s2.0_S2210261222002267.pdf |
| Rights: | http://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: | edsbas.468B517B |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |