Academic Journal
Nonsteroidal anti-inflammatory drug-induced colopathy: An uncommon cause of positive immunochemical faecal occult blood test in the program for colorectal cancer screening
| العنوان: | Nonsteroidal anti-inflammatory drug-induced colopathy: An uncommon cause of positive immunochemical faecal occult blood test in the program for colorectal cancer screening |
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| المؤلفون: | Smolović Brigita, Vučković Ljiljana, Borozan Sanja, Vukčević Batrić |
| المصدر: | Vojnosanitetski Pregled, Vol 78, Iss 1, Pp 105-108 (2021) |
| بيانات النشر: | Military Health Department, Ministry of Defance, Serbia |
| سنة النشر: | 2021 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | colorectal neoplasms, diagnosis, feces, occult blood, colonic diseases, anti-inflammatory agents, treatment outcome, Medicine (General), R5-920 |
| الوصف: | Introduction. Nonsteroidal anti-inflammatory drug-induced colopathy is an uncommon condition associated with the long-term use of enteric-coated and slow-release nonsteroidal anti-inflammatory drugs. This paper presents a case of colopathy showing no symptoms or signs, discovered by a positive immunochemical faecal occult blood test. Case report. Performed within the framework of the National Program for Screening of Colorectal Cancer, the immunochemical faecal occult blood test was positive in a 56-year-old female patient. The colonoscopy revealed three lesions in the right colon: one erosion-ulceration and two concentric "diaphragm-like" strictures passable by the endoscope. The patient reported that she had been taking diclofenac 100 mg twice a day for the past seven years. After withdrawing the offending drug, the second colonoscopy indicated a marked improvement in the colonic mucosa while the "diaphragm-like" strictures persisted. Conclusion. The cases of nonsteroidal anti-inflammatory drug-induced colopathy are likely to become more frequent. It would be, therefore, advisable to consider the long-term u se of such d rugs as being a possible f actor that leads to mucosal injury, particularly in the right colon, as well as being a rare reason for a positive immunochemical faecal occult blood test. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English Serbian |
| تدمد: | 0042-8450 2406-0720 |
| Relation: | https://doaj.org/toc/0042-8450; https://doaj.org/toc/2406-0720; https://doaj.org/article/f4a45b0fa5924814870c0fe53c83d872 |
| DOI: | 10.2298/VSP181004004S |
| الاتاحة: | https://doi.org/10.2298/VSP181004004S https://doaj.org/article/f4a45b0fa5924814870c0fe53c83d872 |
| رقم الانضمام: | edsbas.46371EFB |
| قاعدة البيانات: | BASE |
| تدمد: | 00428450 24060720 |
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| DOI: | 10.2298/VSP181004004S |