Academic Journal

Antibacterial Property of Composites of Reduced Graphene Oxide with Nano-Silver and Zinc Oxide Nanoparticles Synthesized Using a Microwave-Assisted Approach

التفاصيل البيبلوغرافية
العنوان: Antibacterial Property of Composites of Reduced Graphene Oxide with Nano-Silver and Zinc Oxide Nanoparticles Synthesized Using a Microwave-Assisted Approach
المؤلفون: Yi-Huang Hsueh, Chien-Te Hsieh, Shu-Ting Chiu, Ping-Han Tsai, Chia-Ying Liu, Wan-Ju Ke
المصدر: International Journal of Molecular Sciences; Volume 20; Issue 21; Pages: 5394
بيانات النشر: Multidisciplinary Digital Publishing Institute
سنة النشر: 2019
المجموعة: MDPI Open Access Publishing
مصطلحات موضوعية: antibacterial agents, Escherichia coli, graphene, minimum inhibitory concentration, nanocomposite, nano-silver, Staphylococcus aureus, sterilization
جغرافية الموضوع: agris
الوصف: Graphene oxide (GO) composites with various metal nanoparticles (NPs) are attracting increasing interest owing to their broad scope in biomedical applications. Here, microwave-assisted chemical reduction was used to deposit nano-silver and zinc oxide NPs (Ag and ZnO NPs) on the surface of reduced GO (rGO) at the following weight percentages: 5.34% Ag/rGO, 7.49% Ag/rGO, 6.85% ZnO/rGO, 16.45% ZnO/rGO, 3.47/34.91% Ag/ZnO/rGO, and 7.08/15.28% Ag/ZnO/rGO. These materials were tested for antibacterial activity, and 3.47/34.91% Ag/ZnO/rGO and 7.08/15.28% Ag/ZnO/rGO exhibited better antibacterial activity than the other tested materials against the gram-negative bacterium Escherichia coli K12. At 1000 ppm, both these Ag/ZnO/rGO composites had better killing properties against both E. coli K12 and the gram-positive bacterium Staphylococcus aureus SA113 than Ag/rGO and ZnO/rGO did. RedoxSensor flow cytometry showed that 3.47/34.91% Ag/ZnO/rGO and 7.08/15.28% Ag/ZnO/rGO decreased reductase activity and affected membrane integrity in the bacteria. At 100 ppm, these two composites affected membrane integrity more in E. coli, while 7.08/15.28% Ag/ZnO/rGO considerably decreased reductase activity in S. aureus. Thus, the 3.47/34.91% and 7.08%/15.28% Ag/ZnO/rGO nanocomposites can be applied not only as antibacterial agents but also in a variety of biomedical materials such as sensors, photothermal therapy, drug delivery, and catalysis, in the future.
نوع الوثيقة: text
وصف الملف: application/pdf
اللغة: English
Relation: Materials Science; https://dx.doi.org/10.3390/ijms20215394
DOI: 10.3390/ijms20215394
الاتاحة: https://doi.org/10.3390/ijms20215394
Rights: https://creativecommons.org/licenses/by/4.0/
رقم الانضمام: edsbas.44DD2D52
قاعدة البيانات: BASE