Academic Journal
Pure and Mixed Tubular Carcinoma of the Breast: Mammographic Features, Clinicopathological Characteristics and Prognostic Analysis
| العنوان: | Pure and Mixed Tubular Carcinoma of the Breast: Mammographic Features, Clinicopathological Characteristics and Prognostic Analysis |
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| المؤلفون: | Wen, Chanjuan, Xu, Weimin, Qin, Genggeng, Zeng, Hui, He, Zilong, Wang, Sina, Xu, Zeyuan, Ma, Mengwei, Luo, Zhendong, Chen, Weiguo |
| المساهمون: | Natural Science Foundation of Guangdong Province, China, Clinical Research Program of Nanfang Hospital, Southern Medical University |
| المصدر: | Technology in Cancer Research & Treatment ; volume 20 ; ISSN 1533-0346 1533-0338 |
| بيانات النشر: | SAGE Publications |
| سنة النشر: | 2021 |
| الوصف: | Objective: To evaluate the mammographic features, clinicopathological characteristics, treatments, and prognosis of pure and mixed tubular carcinomas of the breast. Materials and methods: Twenty-five tubular carcinomas were pathologically confirmed at our hospital from January 2011 to May 2019. Twenty-one patients underwent preoperative mammography. A retrospective analysis of mammographic features, clinicopathological characteristics, treatment, and outcomes was performed. Results: Altogether, 95% of the pure tubular carcinomas (PTCs) and mixed tubular carcinomas (MTCs) showed the presence of a mass or structural distortions on mammography and the difference was not statistically significant ( P = .373). MTCs exhibited a larger tumor size than PTCs ( P = .033). Lymph node metastasis was more common ( P = .005) in MTCs. Patients in our study showed high estrogen receptor and progesterone receptor positivity rates, but low human epidermal growth factor receptor 2 positivity rate. The overall survival rate was 100% in both PTC and MTC groups and the 5-year disease-free survival rates were 100% and 75%, respectively with no significant difference between the groups ( P = .264). Conclusion: Tubular carcinoma of the breast is potentially malignant and has a favorable prognosis. Digital breast tomosynthesis may improve its detection. For patients with PTC, breast-conserving surgery and sentinel lymph node biopsy are recommended based on the low rate of lymph node metastasis and good prognosis. MTC has a relatively high rate of lymph node metastasis and a particular risk of metastasis. Axillary lymph node dissection should be performed for MTC even if the tumor is smaller than 2 cm. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1177/15330338211045198 |
| الاتاحة: | https://doi.org/10.1177/15330338211045198 https://journals.sagepub.com/doi/pdf/10.1177/15330338211045198 https://journals.sagepub.com/doi/full-xml/10.1177/15330338211045198 |
| Rights: | https://creativecommons.org/licenses/by-nc/4.0/ |
| رقم الانضمام: | edsbas.4494FE99 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1177/15330338211045198 |
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