Academic Journal
Impaired muscle stem cell function in cows with high concentrations of androstenedione in their follicular fluid
| العنوان: | Impaired muscle stem cell function in cows with high concentrations of androstenedione in their follicular fluid |
|---|---|
| المؤلفون: | Barnes, Taylor L., Beede, Kiristen A., Merrick, Elena M., Cadaret, Caitlin N., Cupp, Andrea S., Yates, Dustin T |
| المصدر: | Faculty Papers and Publications in Animal Science |
| بيانات النشر: | DigitalCommons@University of Nebraska - Lincoln |
| سنة النشر: | 2018 |
| المجموعة: | University of Nebraska-Lincoln: DigitalCommons@UNL |
| مصطلحات موضوعية: | Animal Sciences, Genetics and Genomics, Meat Science |
| الوصف: | It is unclear whether androstenedione (A4) increases muscle mass and strength similar to testosterone or whether it produces primarily catabolic effects on muscle-like estrogen (Rasmussen et al., 2000). Summers et al. (2014) observed two populations of cows that exhibit either high (>40 ng/mL; High A4) or low (<20 ng/mL; Low A4) concentrations of A4 within the fluid of the dominant follicle just prior to ovulation. High A4 cows had decreased reproductive rates and shorter times before falling out of the herd, but those that did produce calves weaned them ~10-kg heavier than their low A4 counterparts (Summers et al., 2014). It appears that the difference in weights is due to faster growing and more efficient skeletal muscle. High A4 cows share many characteristics with women suffering from polycystic ovary syndrome (PCOS), whose high levels of circulating androgens are associated with changes in body composition (Kirchengast and Huber, 2001). |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | unknown |
| Relation: | https://digitalcommons.unl.edu/animalscifacpub/1041; https://digitalcommons.unl.edu/context/animalscifacpub/article/2056/viewcontent/Barnes_TAS_2018_Impaired_muscle_stem.pdf |
| الاتاحة: | https://digitalcommons.unl.edu/animalscifacpub/1041 https://digitalcommons.unl.edu/context/animalscifacpub/article/2056/viewcontent/Barnes_TAS_2018_Impaired_muscle_stem.pdf |
| رقم الانضمام: | edsbas.447277AB |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |