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Diet and Nutraceutical Supplementation in Dyslipidemic Patients: First Results of an Italian Single Center Real-World Retrospective Analysis

التفاصيل البيبلوغرافية
العنوان: Diet and Nutraceutical Supplementation in Dyslipidemic Patients: First Results of an Italian Single Center Real-World Retrospective Analysis
المؤلفون: Andrea Pasta, Elena Formisano, Anna Laura Cremonini, Elio Maganza, Erika Parodi, Sabrina Piras, Livia Pisciotta
المصدر: Nutrients, Vol 12, Iss 2056, p 2056 (2020)
بيانات النشر: MDPI AG
سنة النشر: 2020
المجموعة: Directory of Open Access Journals: DOAJ Articles
مصطلحات موضوعية: lipid lowering diet, nutraceutical supplements, dyslipidemias, hypercholesterolemia, hypertriglyceridemia, EAS/ESC guidelines LDL-C targets, Nutrition. Foods and food supply, TX341-641
الوصف: Background: Dyslipidemias are a heterogeneous group of metabolic disorders mainly characterized by an increased risk of atherosclerotic cardiovascular disease (ASCVD) or other conditions, such as acute pancreatitis in hypertriglyceridemia. The aim of this study was to evaluate the effect of diet treatment and nutraceutical (NUTs) supplementation on the plasma lipid profile in outpatient dyslipidemic subjects, considering the influence of several factors (i.e., gender, age, body mass index, alcohol consumption, and smoking habits). Methods: 487 dyslipidemic patients spanning from 2015 to 2019 were treated with a Mediterranean diet or NUTs in a real-word setting and were retrospectively analyzed. General characteristics and lipid profile at baseline and after the follow-up period were evaluated. Results: Diet alone reduced total cholesterol (−19 mg/dL, −7.7%), LDL cholesterol (−18 mg/dL, −10.1%), and triglycerides (−20 mg/dL, −16.7%). Triglycerides (TG) decreased more in men, while women were associated with higher reduction of LDL cholesterol (LDL-C). Different types of NUTs further ameliorate lipid profiles when associated with diet. Nevertheless, most patients at low ASCVD risk (222 out of 262, 81.6%) did not achieve the 2019 ESC/EAS guidelines recommended LDL-C goals (i.e., LDL-C < 116 mg/dL). Conclusion: Lipid-lowering diet improves lipid profile, and NUTs can boost its efficacy, but taken together they are mainly unsatisfactory with respect to the targets imposed by 2019 EAS/ESC guidelines.
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 2072-6643
Relation: https://www.mdpi.com/2072-6643/12/7/2056; https://doaj.org/toc/2072-6643; https://doaj.org/article/b394d561208c4236b93921bc7f339c36
DOI: 10.3390/nu12072056
الاتاحة: https://doi.org/10.3390/nu12072056
https://doaj.org/article/b394d561208c4236b93921bc7f339c36
رقم الانضمام: edsbas.43C3685C
قاعدة البيانات: BASE
الوصف
تدمد:20726643
DOI:10.3390/nu12072056