Academic Journal
ESPGHAN recommendations on treatment of chronic hepatitis C virus infection in adolescents and children including those living in resourceâ€limited settings
| العنوان: | ESPGHAN recommendations on treatment of chronic hepatitis C virus infection in adolescents and children including those living in resourceâ€limited settings |
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| المؤلفون: | Indolfi, Giuseppe, Gonzalezâ€Peralta, Regino P., Jonas, Maureen M., Sayed, Manal Hamdyâ€El, Fischler, Björn, Sokal, Etienne, Wirth, Stefan, Stéphenne, Xavier, Nicastro, Emmanuel |
| المساهمون: | UCL - SSS/IREC/PEDI - Pôle de Pédiatrie, UCL - (SLuc) Service de gastro-entérologie et hépatologie pédiatrique |
| المصدر: | Journal of Pediatric Gastroenterology and Nutrition, Vol. 78, no.4, p. 957-972 (2024) |
| بيانات النشر: | Wiley |
| سنة النشر: | 2024 |
| المجموعة: | DIAL@USL-B (Université Saint-Louis, Bruxelles) |
| مصطلحات موضوعية: | Gastroenterology, Pediatrics, Perinatology and Child Health |
| الوصف: | Hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide, with more than three million viraemic adolescents and children. Treatment of adults with HCV infection and HCV-related liver disease has advanced considerably thanks to development and improvements in therapy. Direct-acting antiviral regimens are safe and effective. Three regimens with pangenotypic activity (glecaprevir/pibrentasvir, sofosbuvir/velpatasvir and sofosbuvir/velpatasvir/voxilaprevir) and three regimens with genotype-specific activity (sofosbuvir/ribavirin, sofosbuvir/ledipasvir and elbasvir/grazoprevir) have been approved with age-specific limitation for treatment of children with chronic hepatitis C by the European Medicines Agency and the United States Food and Drug Administration. The World Health Organization has set the ambitious target to eliminate hepatitis C as a major public health threat by 2030 and based its actions against HCV on the large use of direct acting antivirals. These updated European Society for Pediatric Gastroenterology, Hepatology and Nutrition recommendations on treatment of hepatitis C describe the optimal therapeutic management of adolescents and children with HCV infection including specific indications for those living in resource-limited settings. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0277-2116 1536-4801 |
| Relation: | boreal:286735; http://hdl.handle.net/2078.1/286735; urn:ISSN:0277-2116; urn:EISSN:1536-4801 |
| DOI: | 10.1002/jpn3.12160 |
| الاتاحة: | http://hdl.handle.net/2078.1/286735 https://doi.org/10.1002/jpn3.12160 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.42FCFCA |
| قاعدة البيانات: | BASE |
| تدمد: | 02772116 15364801 |
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| DOI: | 10.1002/jpn3.12160 |