التفاصيل البيبلوغرافية
| العنوان: |
Figure 3 from: Abbas AH, Mahmood AAR, Tahtamouni LH, Al-Mazaydeh ZA, Rammaha MS, Alsoubani F, Al-bayati RI (2021) A novel derivative of picolinic acid induces endoplasmic reticulum stress-mediated apoptosis in human non-small cell lung cancer cells: synthesis, docking study, and anticancer activity. Pharmacia 68(3): 679-692. https://doi.org/10.3897/pharmacia.68.e70654 |
| المؤلفون: |
Abbas, Ali H., Mahmood, Ammar A. Razzak, Tahtamouni, Lubna H., Al-Mazaydeh, Zainab A., Rammaha, Majdoleen S., Alsoubani, Fatima, Al-bayati, Rheda I. |
| بيانات النشر: |
Zenodo |
| سنة النشر: |
2021 |
| المجموعة: |
Zenodo |
| مصطلحات موضوعية: |
Picolinic acid, ER stress pathway, Docking, A549 lung cancer cells |
| الوصف: |
Figure 3 Compound 5 induces apoptosis in A549 lung cancer cells. A) Fluorescence images of A549 lung cancer cells showing fragmented nuclei after DAPI staining. Scale bar: 10 µm, B) Detection of DNA fragmentation by agarose gel electrophoresis. Cells were treated and genomic DNA was extracted and electrophoresed on 1.5% agarose gels. M: DNA molecular weight marker; C: vehicle-treated control cells; 1%: 1% DMSO-treated cells; 5%: 5% DMSO-treated cells; C.5: Compound 5-treated cells. Arrows indicate DNA fragments. Three experiments were performed with similar results. |
| نوع الوثيقة: |
other/unknown material |
| اللغة: |
unknown |
| Relation: |
https://doi.org/10.3897/pharmacia.68.e70654; https://doi.org/10.3897/pharmacia.68.e70654.figure3; oai:zenodo.org:5511037 |
| DOI: |
10.3897/pharmacia.68.e70654.figure3 |
| الاتاحة: |
https://doi.org/10.3897/pharmacia.68.e70654.figure3 |
| Rights: |
info:eu-repo/semantics/openAccess ; Creative Commons Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/legalcode |
| رقم الانضمام: |
edsbas.42D436B4 |
| قاعدة البيانات: |
BASE |