Academic Journal
Structures of Rhodopseudomonas palustris RC-LH1 complexes with open or closed quinone channels
| العنوان: | Structures of Rhodopseudomonas palustris RC-LH1 complexes with open or closed quinone channels |
|---|---|
| المؤلفون: | Swainsbury, D.J.K., Qian, P., Jackson, P.J., Faries, K.M., Niedzwiedzki, D.M., Martin, E.C., Farmer, D.A., Malone, L.A., Thompson, R.F., Ranson, N.A., Canniffe, D.P., Dickman, M.J., Holten, D., Kirmaier, C., Hitchcock, A., Hunter, C.N. |
| بيانات النشر: | American Association for the Advancement of Science (AAAS) |
| سنة النشر: | 2021 |
| المجموعة: | White Rose Research Online (Universities of Leeds, Sheffield & York) |
| الوصف: | The reaction-center light-harvesting complex 1 (RC-LH1) is the core photosynthetic component in purple phototrophic bacteria. We present two cryo–electron microscopy structures of RC-LH1 complexes from Rhodopseudomonas palustris. A 2.65-Å resolution structure of the RC-LH114-W complex consists of an open 14-subunit LH1 ring surrounding the RC interrupted by protein-W, whereas the complex without protein-W at 2.80-Å resolution comprises an RC completely encircled by a closed, 16-subunit LH1 ring. Comparison of these structures provides insights into quinone dynamics within RC-LH1 complexes, including a previously unidentified conformational change upon quinone binding at the RC QB site, and the locations of accessory quinone binding sites that aid their delivery to the RC. The structurally unique protein-W prevents LH1 ring closure, creating a channel for accelerated quinone/quinol exchange. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | text |
| اللغة: | English |
| Relation: | https://eprints.whiterose.ac.uk/170926/1/eabe2631.full.pdf; Swainsbury, D.J.K. orcid.org/0000-0002-0754-0363 , Qian, P., Jackson, P.J. orcid.org/0000-0001-9671-2472 et al. (13 more authors) (2021) Structures of Rhodopseudomonas palustris RC-LH1 complexes with open or closed quinone channels. Science Advances, 7 (3). eabe2631. ISSN 2375-2548 |
| الاتاحة: | https://eprints.whiterose.ac.uk/170926/ https://eprints.whiterose.ac.uk/170926/1/eabe2631.full.pdf |
| Rights: | cc_by_4 |
| رقم الانضمام: | edsbas.42C6B2C4 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |