Academic Journal
Lactate/albumin ratio prognostic value for mortality in patients older than 65 years with complicated urinary tract infection = Valor pronóstico del cociente lactato/albúmina para la mortalidad en pacientes mayores de 65 años con infección urinaria complicada
العنوان: | Lactate/albumin ratio prognostic value for mortality in patients older than 65 years with complicated urinary tract infection = Valor pronóstico del cociente lactato/albúmina para la mortalidad en pacientes mayores de 65 años con infección urinaria complicada |
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المؤلفون: | Madrazo López, Manuel, López Cruz, Ian, Piles, Laura, Alberola Enguídanos, Juan, Micó Gandia, Jaume, Eiros, José María, Artero Mora, Arturo |
المصدر: | Madrazo López, Manuel López Cruz, Ian Piles, Laura Alberola Enguídanos, Juan Micó Gandia, Jaume Eiros, José María Artero Mora, Arturo 2023 Lactate/albumin ratio prognostic value for mortality in patients older than 65 years with complicated urinary tract infection = Valor pronóstico del cociente lactato/albúmina para la mortalidad en pacientes mayores de 65 años con infección urinaria complicada Revista Clínica Española 223 6 366 370 |
سنة النشر: | 2024 |
المجموعة: | Universitat de València: Roderic - Repositorio de contenido libre |
مصطلحات موضوعية: | aparell urinari, infecció, persones grans |
الوصف: | Background Lactate to albumin ratio (LAR) is an emerging sepsis biomarker that has been tested for mortality in patients with sepsis of different focus. Our goal is to evaluate the prognostic value of LAR in patients admitted to the hospital due to complicated urinary tract infections. Methods Prospective observational study of patients older than 65 years diagnosed with UTI. Area under the ROC curve, sensibility, and specificity to predict 30-day mortality were calculated for LAR, qSOFA and SOFA. Results 341 UTI cases were analyzed. 30-day mortality (20.2% vs. 6.7%, p < 0.001) and longer hospital stay (5 [4-8] vs. 4 [3-7], p 0.018) were associated with LAR ≥ 0.708. LAR has no statistically significant differences compared to qSOFA and SOFA for predicting 30-day mortality (AUROC 0.737 vs. 0.832 and 0.777 respectively, p 0.119 and p 0.496). The sensitivity of LAR was similar to the sensitivity of qSOFA and SOFA (60.8% vs. 84.4% and 82.2, respectively, p 0.746 and 0.837). However, its specificity was lower than the specificity of qSOFA (60.8% vs. 75%, p 0.003), but similar to the specificity of SOFA (60.8% vs. 57.8%, p 0.787). Conclusion LAR has no significant differences with other well-stablished scores in sepsis, such as qSOFA and SOFA, to predict 30-day mortality in patients with complicated UTI. |
نوع الوثيقة: | article in journal/newspaper |
وصف الملف: | application/pdf |
اللغة: | English |
Relation: | Revista Clínica Española, 2023, vol. 223, num. 6, p. 366-370; https://hdl.handle.net/10550/102003; 158588 |
DOI: | 10.1016/j.rceng.2023.04.006 |
الاتاحة: | https://hdl.handle.net/10550/102003 https://doi.org/10.1016/j.rceng.2023.04.006 |
Rights: | metadata only access |
رقم الانضمام: | edsbas.41E62582 |
قاعدة البيانات: | BASE |
DOI: | 10.1016/j.rceng.2023.04.006 |
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