Academic Journal
Pathogenetic Mechanisms of Organ Dysfunction in Severe Concomitant Trauma ; Патогенетические механизмы органной дисфункции при тяжелой сочетанной травме
| العنوان: | Pathogenetic Mechanisms of Organ Dysfunction in Severe Concomitant Trauma ; Патогенетические механизмы органной дисфункции при тяжелой сочетанной травме |
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| المؤلفون: | G. V. Bulava, Г. В. Булава |
| المصدر: | Russian Sklifosovsky Journal "Emergency Medical Care"; Том 12, № 1 (2023); 92-98 ; Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь»; Том 12, № 1 (2023); 92-98 ; 2541-8017 ; 2223-9022 |
| بيانات النشر: | “N.V. Sklifosovsky Research Institute for Emergency Medicine” |
| سنة النشر: | 2023 |
| المجموعة: | Sklifosovsky Journal "Emergency Medical Care" / Журнал им. Н.В. Склифосовского «Неотложная медицинская помощь» |
| مصطلحات موضوعية: | микробиом, acute blood loss, systemic inflammatory reaction, cytokines, traumatic brain injury, microbiome, острая кровопотеря, системная воспалительная реакция, цитокины, черепно-мозговая травма |
| الوصف: | Severe concomitant trauma has been a major demographic and medical problem for many years, being the cause of high mortality of the able-bodied population. The simultaneous formation of an array of destroyed tissues triggers a systemic inflammatory reaction, which, against the background of traumatic and hemorrhagic shock, leads to an imbalance in immune reactivity and predisposes to the development of septic complications. The review presents the basic concepts of post-traumatic reactions and violations of the balance of cellular and humoral immune mechanisms leading to the development of complications. ; Тяжелая сочетанная травма на протяжении многих лет представляет собой большую демографическую и медицинскую проблему, являясь причиной высокой смертности трудоспособного населения. Одномоментное образование массива разрушенных тканей «запускает» системную воспалительную реакцию, которая на фоне травматического и геморрагического шока приводит к дисбалансу иммунной реактивности и предрасполагает к развитию септических осложнений. В обзоре представлены основные понятия о посттравматических реакциях и нарушениях баланса клеточных и гуморальных иммунных механизмов, приводящих к развитию осложнений. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | Russian |
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| DOI: | 10.23934/2223-9022-2023-12-1-92-98 |
| الاتاحة: | https://www.jnmp.ru/jour/article/view/1574 https://doi.org/10.23934/2223-9022-2023-12-1-92-98 |
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| رقم الانضمام: | edsbas.3FFEACA4 |
| قاعدة البيانات: | BASE |
| DOI: | 10.23934/2223-9022-2023-12-1-92-98 |
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