Academic Journal
Maternal and Neonatal Outcomes in Pregnant Women With Coronavirus Disease 2019 in Korea
العنوان: | Maternal and Neonatal Outcomes in Pregnant Women With Coronavirus Disease 2019 in Korea |
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المؤلفون: | Chung, Y, Kim, EJ, Kim, HS, Park, KH, Baek, JH, Kim, J, Lee, JY, Lee, CS, Lim, S, Kim, SW, Kim, ES, Shi, HJ, Hong, SH, Jun, JB, Hong, KW, Choi, JP, Yang, KS, Yoon, YK |
المساهمون: | 111115, Kim, EJ |
سنة النشر: | 2022 |
مصطلحات موضوعية: | Cesarean Section, COVID-19, COVID-19 Testing, Female, Humans, Infant, Newborn, Infectious Disease Transmission, Vertical, Pregnancy, Pregnancy Complications, Infectious, Pregnancy Outcome, Pregnant Women, Premature Birth, RNA-Directed DNA Polymerase, Coronavirus disease 2019, Neonate, Severe acute respiratory syndrome coronavirus 2 |
الوصف: | BACKGROUND: This study aimed to describe the maternal, obstetrical, and neonatal outcomes in pregnant women with coronavirus disease 2019 (COVID-19) and identify the predictors associated with the severity of COVID-19. METHODS: This multicenter observational study included consecutive pregnant women admitted because of COVID-19 confirmed using reverse transcriptase-polymerase chain reaction (RT-PCR) test at 15 hospitals in the Republic of Korea between January 2020 and December 2021. RESULTS: A total of 257 women with COVID-19 and 62 newborns were included in this study. Most of the patients developed this disease during the third trimester. Nine patients (7.4%) developed pregnancy-related complications. All pregnant women received inpatient treatment, of whom 9 (3.5%) required intensive care, but none of them died. The gestational age at COVID-19 diagnosis (odds ratio [OR], 1.096, 95% confidence interval [CI], 1.04-1.15) and parity (OR, 1.703, 95% CI, 1.13-2.57) were identified as significant risk factors of severe diseases. Among women who delivered, 78.5% underwent cesarean section. Preterm birth (38.5%), premature rupture of membranes (7.7%), and miscarriage (4.6%) occurred, but there was no stillbirth or neonatal death. The RT-PCR test of newborns' amniotic fluid and umbilical cord blood samples was negative for severe acute respiratory syndrome coronavirus 2. CONCLUSION: At the time of COVID-19 diagnosis, gestational age and parity of pregnant women were the risk factors of disease severity. Vertical transmission of COVID-19 was not observed, and maternal severity did not significantly affect the neonatal prognosis. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 1011-8934 1598-6357 |
Relation: | J010118934; http://repository.ajou.ac.kr/handle/201003/24654; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592939; Journal of Korean medical science, 37(41). : e297-e297, 2022 |
DOI: | 10.3346/jkms.2022.37.e297 |
الاتاحة: | http://repository.ajou.ac.kr/handle/201003/24654 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9592939 https://doi.org/10.3346/jkms.2022.37.e297 |
رقم الانضمام: | edsbas.3EF9B54D |
قاعدة البيانات: | BASE |
تدمد: | 10118934 15986357 |
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DOI: | 10.3346/jkms.2022.37.e297 |