Academic Journal
Sex-dependent impact of perinatal 5G electromagnetic field exposure in the adolescent rat behavior
| العنوان: | Sex-dependent impact of perinatal 5G electromagnetic field exposure in the adolescent rat behavior |
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| المؤلفون: | Bodin, Raphaël, Seewooruttun, Chandreshwar, Corona, Aurélie, Delanaud, Stéphane, Pelletier, Amandine, Villégier, Anne-Sophie |
| المساهمون: | Institut National de la Santé et de la Recherche Médicale (INSERM), Périnatalité et Risques Toxiques - UMR INERIS_I 1 UPJV (PERITOX), Institut National de l'Environnement Industriel et des Risques (INERIS)-Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, Institut National de l'Environnement Industriel et des Risques (INERIS) |
| المصدر: | ISSN: 0944-1344. |
| بيانات النشر: | HAL CCSD Springer Verlag |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | 5G communications, Behavioural tests, Electromagnetic radiation, Incisors eruption, Neurodevelopment, Radiofrequency fields, [SDV]Life Sciences [q-bio] |
| الوصف: | International audience ; The fifth generation (5G) network is currently being worldwide spread out, raising questions about the potential impact of this new technology, particularly on immature organisms. The current study aimed to investigate the effects of daily 5G electromagnetic field (EMF) perinatal exposure on the neurodevelopment of rats. The exposure level was set to the limit of whole-body public exposure defined by the International Commission on Non-Ionizing Radiation Protection. The mother rat specific absorption rate (SAR) was 0.07 W/kg for 22 h/day at 3500 MHz continuous wave from gestational day (GD) 8 to post-natal day (PND) 21. Clinical observations were performed on weight, length, sex ratio, number of pups per litter, and number of stillborn in sham and EMF-exposed groups (n = 7). The age of pinna ear detachment, incisor eruption, and eye opening were recorded. Behavior was assessed on righting, gripping, and negative geotaxis reflexes at PND 3 or 7 and on stereotyped and horizontal movements in the open field at PND 43. Our results indicated that both male and female pups showed delayed incisor eruption in the EMF-exposed group compared to the sham group (+ 1 day). Regarding activity in the open field, adolescent females showed less stereotyped movements (- 70%), while adolescent males showed more stereotyped movements (+ 50%) compared to the sham-exposed adolescent rats. Thus, the present study suggested that perinatal exposure to 5G at SAR level below reglementary threshold led to perturbations in the descendants seen in juveniles and adolescents. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | hal-04250387; https://u-picardie.hal.science/hal-04250387; https://u-picardie.hal.science/hal-04250387/document; https://u-picardie.hal.science/hal-04250387/file/2023-158%20post-print.pdf |
| DOI: | 10.1007/s11356-023-30256-7 |
| الاتاحة: | https://u-picardie.hal.science/hal-04250387 https://u-picardie.hal.science/hal-04250387/document https://u-picardie.hal.science/hal-04250387/file/2023-158%20post-print.pdf https://doi.org/10.1007/s11356-023-30256-7 |
| Rights: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.3EF383CF |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s11356-023-30256-7 |
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