Academic Journal
New ent-clerodane and abietane diterpenoids from the roots of Kenyan croton megalocarpoides Friis & M. G. Gilbert
| العنوان: | New ent-clerodane and abietane diterpenoids from the roots of Kenyan croton megalocarpoides Friis & M. G. Gilbert |
|---|---|
| المؤلفون: | Ndunda, Beth, Langat, Moses K., Mulholland, Dulcie A., Eastman, Harry, Jacob, Melissa R., Khan, Shabana I., Walker, Larry A., Muhammad, Ilias, Kerubo, Leonidah O., Midiwo, Jacob O. |
| بيانات النشر: | University of Nairobi |
| سنة النشر: | 2016 |
| المجموعة: | University of Nairobi Digital Repository |
| مصطلحات موضوعية: | Croton megalocarpoides - Euphorbiaceae - abietane - ent-clerodane - ent-trachylobane - diterpenoids - electronic circular dichroism |
| الوصف: | The roots of the endangered medicinal plant Croton megalocarpoides collected in Kenya were investigated and twenty-two compounds isolated. Among them were twelve new ent-clerodane (1–12) and a new abietane (13) diterpenoids, alongside the known crotocorylifuran (4 a), two known abietane and four known ent-trachylobane diterpenoids, and the triterpenoids, lupeol and acetyl aleurotolic acid. The structures of the compounds were determined using NMR, HRMS and ECD. The isolated compounds were evaluated against a series of microorganisms (fungal and bacteria) and also against Plasmodium falciparum, however no activity was observed. # Key words Croton megalocarpoides - Euphorbiaceae - abietane - ent-clerodane - ent-trachylobane - diterpenoids - electronic circular dichroism |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | Ndunda, Beth, et al. "New ent-Clerodane and Abietane Diterpenoids from the Roots of Kenyan Croton megalocarpoides Friis & MG Gilbert." Planta medica 82.11/12 (2016): 1079-1086.; https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0042-108857; http://hdl.handle.net/11295/100737 |
| DOI: | 10.1055/s-0042-108857 |
| الاتاحة: | http://hdl.handle.net/11295/100737 https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0042-108857 |
| Rights: | Attribution-NonCommercial-NoDerivs 3.0 United States ; http://creativecommons.org/licenses/by-nc-nd/3.0/us/ |
| رقم الانضمام: | edsbas.3EEB2C1F |
| قاعدة البيانات: | BASE |
| DOI: | 10.1055/s-0042-108857 |
|---|