Academic Journal
Moderate influenza vaccine effectiveness against hospitalisation with A(H3N2) and A(H1N1) influenza in 2013–14: Results from the InNHOVE network
| العنوان: | Moderate influenza vaccine effectiveness against hospitalisation with A(H3N2) and A(H1N1) influenza in 2013–14: Results from the InNHOVE network |
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| المؤلفون: | Rondy M., Castilla J., Launay O., Costanzo S., Ezpeleta C., Galtier F., de Gaetano Donati K., Moren A., Beristain X., Chamorro J., Gabari M., Artajo P., Lameiro F., Barrado L., Ortega M., Torres M., Garcia Irure J. J., Irisarri F., Garcia Cenoz M., Guevara M., Casado I., Diaz J., Martinez-Baz I., Lenzi N., Lesieur Z., Bonmarin I., Merle C., Foulongne V., Letois F., Driss V., Geraud P., Bourdin A., Landreau L., Konate A., Corne P., Sebbane M., Klouche K., Leglise M. -S., Loulergue P., Kanaan R., Dumas F., Krivine A., Moncilovic S., Ali N., Duval X., Costa Y., Ait Naman R., Yazdapanah Y., Caseris M., Dournon N., Papo T., Dossier A., Becheur H., Pelletier A. -L., Mal M., Marceau A., Aubier M., Bories R., Casalino E., Choquet C., Houhou N., Vanhems P., Regis C., Jouneau S., Laine F., Tattevin P., Beuzit L., Thebault E., Fey S., Lagathu et Sophie Cha G., Postil D., Alcolea S., Rogez S., Valette M., Lina B., Cauda R., Taccari F., Santangelo R., Perlasca F., Fichera G., Dara M., Iacoviello L., Olivieri M. |
| المساهمون: | Rondy, M., Castilla, J., Launay, O., Costanzo, S., Ezpeleta, C., Galtier, F., de Gaetano Donati, K., Moren, A., Beristain, X., Chamorro, J., Gabari, M., Artajo, P., Lameiro, F., Barrado, L., Ortega, M., Torres, M., Garcia Irure, J. J., Irisarri, F., Garcia Cenoz, M., Guevara, M., Casado, I., Diaz, J., Martinez-Baz, I., Lenzi, N., Lesieur, Z., Bonmarin, I., Merle, C., Foulongne, V., Letois, F., Driss, V., Geraud, P., Bourdin, A., Landreau, L., Konate, A., Corne, P., Sebbane, M., Klouche, K., Leglise, M. -S., Loulergue, P., Kanaan, R., Dumas, F., Krivine, A., Moncilovic, S., Ali, N., Duval, X., Costa, Y., Ait Naman, R., Yazdapanah, Y., Caseris, M., Dournon, N., Papo, T., Dossier, A., Becheur, H., Pelletier, A. -L., Mal, M., Marceau, A., Aubier, M., Bories, R., Casalino, E., Choquet, C., Houhou, N., Vanhems, P., Regis, C., Jouneau, S., Laine, F., Tattevin, P., Beuzit, L., Thebault, E., Fey, S., Lagathu et Sophie Cha, G., Postil, D., Alcolea, S., Rogez, S., Valette, M., Lina, B., Cauda, R., Taccari, F., Santangelo, R., Perlasca, F., Fichera, G., Dara, M., Iacoviello, L., Olivieri, M. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | case control studie, hospital, Influenza, Influenza vaccine, multicentre studies, envir, manag |
| الوصف: | We conducted a multicentre test negative case control study to estimate the 2013–14 influenza vaccine effectiveness (IVE) against hospitalised laboratory confirmed influenza in 12 hospitals in France, Italy and Spain. We included all ≥18years hospitalised patients targeted by local influenza vaccination campaign reporting an influenza-like illness within 7days before admission. We defined as cases patients RT-PCR positive for influenza and as controls those negative for all influenza virus. We used a logistic regression to calculate IVE adjusted for country, month of onset, chronic diseases and age. We included 104 A(H1N1)pdm09, 157 A(H3N2) cases and 585 controls. The adjusted IVE was 42.8% (95%CI: 6.3;65;0) against A(H1N1)pdm09. It was respectively 61.4% (95%CI: −1.9;85.4), 39.4% (95%CI: −32.2;72.2) and 19.7% (95%CI:-148.1;74.0) among patients aged 18–64, 65–79 and ≥80years. The adjusted IVE against A(H3N2) was 38.1% (95%CI: 8.3;58.2) overall. It was respectively 7.8% (95%CI: −145.3;65.4), 25.6% (95%CI: −36.0;59.2) and 55.2% (95%CI: 15.4;76.3) among patients aged 18–64, 65–79 and ≥80years. These results suggest a moderate and age varying effectiveness of the 2013–14 influenza vaccine to prevent hospitalised laboratory-confirmed influenza. While vaccination remains the most effective prevention measure, developing more immunogenic influenza vaccines is needed to prevent severe outcomes among target groups. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | http://hdl.handle.net/11383/2130124 |
| الاتاحة: | http://hdl.handle.net/11383/2130124 |
| Rights: | undefined |
| رقم الانضمام: | edsbas.3DD5122A |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |