التفاصيل البيبلوغرافية
| العنوان: |
Protective Effect of Hesperidin on the Oxidative Stress Induced by an Exhausting Exercise in Intensively Trained Rats |
| المؤلفون: |
Estruel Amades, Seila, Massot Cladera, Malen, Garcia-Cerdà, Pau, Pérez-Cano, Francisco J., Franch i Masferrer, Àngels, Castell, Margarida, Camps i Bossacoma, Mariona |
| المصدر: |
Articles publicats en revistes (Bioquímica i Fisiologia) |
| بيانات النشر: |
MDPI |
| سنة النشر: |
2019 |
| المجموعة: |
Dipòsit Digital de la Universitat de Barcelona |
| مصطلحات موضوعية: |
Condició física, Fatiga, Efecte de l'estrès sobre els animals, Rates (Animals de laboratori), Physical fitness, Fatigue, Effect of stress on animals, Rats as laboratory animals |
| الوصف: |
Intensive exercise can lead to oxidative stress, which can be particularly deleterious for lymphoid tissues. Hesperidin has demonstrated its antioxidant activity, but few studies focus on its influence on intensive training. The aim of this study was to assess the impact of hesperidin on the oxidant/antioxidant status of lymphoid tissues after an intensive training program. Wistar rats were trained for five weeks (five days per week), including two exhaustion tests plus three trainings per week. During this period, animals were orally administrated with 200 mg/kg of hesperidin or vehicle (three days per week). The oxidative status was determined before, immediately after and 24 h after an additional exhaustion test. The production of reactive oxygen species (ROS) by peritoneal macrophages, superoxide dismutase (SOD) and catalase activities in spleen, thymus and liver, and hepatic glutathione peroxidase activity (GPx) were assessed. Hesperidin prevented an increase in ROS production induced by the additional exhaustion test. Likewise, hesperidin avoided a decrease in SOD and catalase activities in the thymus and spleen that was found after the additional exhaustion test. The antioxidant effects of hesperidin were associated with a higher performance in the assessed training model. These results suggest that hesperidin, acting as an antioxidant, can prevent oxidative stress induced by exercise and improve exercise performance. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| تدمد: |
2072-6643 |
| Relation: |
Reproducció del document publicat a: https://doi.org/10.3390/nu11040783; Nutrients, 2019, vol. 11, num. 4; https://doi.org/10.3390/nu11040783; http://hdl.handle.net/2445/168817; 692387 |
| الاتاحة: |
http://hdl.handle.net/2445/168817 |
| Rights: |
cc-by (c) Estruel Amades, Seila et al., 2019 ; http://creativecommons.org/licenses/by/3.0/es ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.3DCBFCD2 |
| قاعدة البيانات: |
BASE |
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