Academic Journal
Binuclear azide-bridged hydrazone Cu(II) complex: Synthesis, characterization and evaluation of biological activity: Scientific paper
| العنوان: | Binuclear azide-bridged hydrazone Cu(II) complex: Synthesis, characterization and evaluation of biological activity: Scientific paper |
|---|---|
| المؤلفون: | Vitomirov, Teodora, Čobeljić, Božidar, Pevec, Andrej, Radanović, Dušanka, Novaković, Irena T., Savić, Milica, Anđelković, Katarina K., Ristović, Maja Šumar |
| المصدر: | Journal of the Serbian Chemical Society |
| بيانات النشر: | Serbian Chemical Society |
| سنة النشر: | 2023 |
| المجموعة: | CHERRY - CHEMistry RepositorY, Faculty of Chemistry, University of Belgrade / Repozitorijum Hemijskog fakulteta - Cherry (Univerzitet u Beogradu - Hemijski fakultet) |
| مصطلحات موضوعية: | Girard’s T reagent, X-ray crystallography, antibacterial activity, anti-fungal activity |
| الوصف: | The condensation product of 7-acetyl-6-azaindole and Girard’s T reagent ((E)-2-(2-(1-(1H-pyrrolo[2,3-c]pyridin-7-yl)ethylidene)hydrazineyl)-N,N,N-trimethyl-2-oxoethan-1-aminium, HL ligand) was used as a ligand in the reaction with Cu(BF4)2·6H2O and NaN3. The reaction led to the formation of a binuclear Cu(II) complex containing two end-to-end (di-m-1,3-N3) azide bridges, as well as two NNO-donor hydrazone ligands, forming an axially elongated square pyramidal geometry around each Cu(II) center. This end-to-end (di-m-1,3-N3) azide bridge binding mode has not yet been reported, in Cu(II) complexes containing the NNO-donor hydrazone ligands, which makes the structure of the complex even more interesting for further studies. The complex was characterized by elemental analysis, IR spectroscopy and X-ray crystallography, and it was found that it crystallizes in the triclinic space group P–1 with the asymmetric unit comprising one Cu(II) centre, zwitterionic ligand L, one azide (N3-) ligand and BF4- counter anion. Examination of antimicrobial activity of the complex shows higher antifungal and antibacterial activity towards tested Gram-positive bacteria in comparison to the hydrazone ligand, with the antifungal activity of the complex even being comparable to the activity of amphotericin B. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1820-7421 |
| Relation: | info:eu-repo/grantAgreement/MESTD/inst-2020/200026/RS//; info:eu-repo/grantAgreement/MESTD/inst-2020/200168/RS//; info:eu-repo/grantAgreement/MESTD/inst-2020/200288/RS//; info:eu-repo/grantAgreement/ScienceFundRS/Ideje/7750288/RS//; Tailoring Molecular Magnets and Catalysts Based on Transition Metal Complexes – TMMagCat; e Slovenian Research Agency (ARRS), grant number P1-0175; http://cherry.chem.bg.ac.rs/handle/123456789/6387; 2-s2.0-85175351026; http://cherry.chem.bg.ac.rs/bitstream/id/34678/Binuclear_pub_2023.pdf |
| DOI: | 10.2298/JSC230623044V |
| الاتاحة: | http://cherry.chem.bg.ac.rs/handle/123456789/6387 https://doi.org/10.2298/JSC230623044V http://cherry.chem.bg.ac.rs/bitstream/id/34678/Binuclear_pub_2023.pdf |
| Rights: | openAccess ; https://creativecommons.org/licenses/by/4.0/ ; BY |
| رقم الانضمام: | edsbas.3CCCB1FC |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 18207421 |
|---|---|
| DOI: | 10.2298/JSC230623044V |