Image
Image_1_Microbial communities of the upper respiratory tract in mild and severe COVID-19 patients: a possible link with the disease course.jpeg
| العنوان: | Image_1_Microbial communities of the upper respiratory tract in mild and severe COVID-19 patients: a possible link with the disease course.jpeg |
|---|---|
| المؤلفون: | Julia S. Galeeva, Elizaveta V. Starikova, Dmitry E. Fedorov, Alexander I. Manolov, Alexander V. Pavlenko, Dmitry N. Konanov, Danil V. Krivonos, Vladislav V. Babenko, Ksenia M. Klimina, Vladimir A. Veselovsky, Maxim D. Morozov, Ilshat R. Gafurov, Raushaniya F. Gaifullina, Vadim M. Govorun, Elena N. Ilina |
| سنة النشر: | 2023 |
| المجموعة: | Frontiers: Figshare |
| مصطلحات موضوعية: | Microbiology, Clinical Microbiology, Dietetics and Nutrigenomics, Microbial Genetics, Microbial Ecology, COVID-19, 16S, human microbiome, oropharyngeal swabs, SARS-CoV-2, upper respiratory tract |
| الوصف: | The microbiota of the respiratory tract remains a relatively poorly studied subject. At the same time, it is involved in modulating the immune response to infectious agents in the host organism, just like the intestinal microbiota. A relationship between the composition of the respiratory microbiota and the likelihood of development and the severity of COVID-19 may be assumed. In this study, we applied the 16S rRNA metagenomic sequencing to analyze the oropharyngeal swabs from 120 COVID-19 patients collected during the first and the second waves of the COVID-19 epidemic in Russia. Differential abundance analysis with respect to comorbidities suggested association of Neisseria oralis, Neisseria mucosa, unidentified Veillonella spp., Lautropia mirabilis species with more severe lung damage, and Streptococcus salivarius, Capnocytophaga sputigena and Haemophilus parahaemolyticus with a milder course of the disease. We hypothesize that the latter bacteria (or some of them) might be beneficial for the respiratory tract and might be able to alleviate the course of the COVID-19 disease. |
| نوع الوثيقة: | still image |
| اللغة: | unknown |
| Relation: | https://figshare.com/articles/figure/Image_1_Microbial_communities_of_the_upper_respiratory_tract_in_mild_and_severe_COVID-19_patients_a_possible_link_with_the_disease_course_jpeg/23255732 |
| DOI: | 10.3389/frmbi.2023.1067019.s001 |
| الاتاحة: | https://doi.org/10.3389/frmbi.2023.1067019.s001 https://figshare.com/articles/figure/Image_1_Microbial_communities_of_the_upper_respiratory_tract_in_mild_and_severe_COVID-19_patients_a_possible_link_with_the_disease_course_jpeg/23255732 |
| Rights: | CC BY 4.0 |
| رقم الانضمام: | edsbas.3B47FAC9 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3389/frmbi.2023.1067019.s001 |
|---|