Academic Journal
Tumor-Homing Peptides as Crucial Component of Magnetic-Based Delivery Systems: Recent Developments and Pharmacoeconomical Perspective
| العنوان: | Tumor-Homing Peptides as Crucial Component of Magnetic-Based Delivery Systems: Recent Developments and Pharmacoeconomical Perspective |
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| المؤلفون: | Sylwia Milewska, Anna Sadowska, Natalia Stefaniuk, Iwona Misztalewska-Turkowicz, Agnieszka Z. Wilczewska, Halina Car, Katarzyna Niemirowicz-Laskowska |
| المصدر: | International Journal of Molecular Sciences, Vol 25, Iss 11, p 6219 (2024) |
| بيانات النشر: | MDPI AG |
| سنة النشر: | 2024 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | tumor-homing peptides, targeted delivery, targeting ligands, delivery systems, anticancer therapy, pharmacoeconomics, Biology (General), QH301-705.5, Chemistry, QD1-999 |
| الوصف: | According to data from the World Health Organization (WHO), cancer is considered to be one of the leading causes of death worldwide, and new therapeutic approaches, especially improved novel cancer treatment regimens, are in high demand. Considering that many chemotherapeutic drugs tend to have poor pharmacokinetic profiles, including rapid clearance and limited on-site accumulation, a combined approach with tumor-homing peptide (THP)-functionalized magnetic nanoparticles could lead to remarkable improvements. This is confirmed by an increasing number of papers in this field, showing that the on-target peptide functionalization of magnetic nanoparticles improves their penetration properties and ensures tumor-specific binding, which results in an increased clinical response. This review aims to highlight the potential applications of THPs in combination with magnetic carriers across various fields, including a pharmacoeconomic perspective. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1422-0067 1661-6596 |
| Relation: | https://www.mdpi.com/1422-0067/25/11/6219; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/f2b1c73dca694f33832f710fe95704b4 |
| DOI: | 10.3390/ijms25116219 |
| الاتاحة: | https://doi.org/10.3390/ijms25116219 https://doaj.org/article/f2b1c73dca694f33832f710fe95704b4 |
| رقم الانضمام: | edsbas.3B2AF1DF |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 14220067 16616596 |
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| DOI: | 10.3390/ijms25116219 |