التفاصيل البيبلوغرافية
| العنوان: |
ATTRv in Lazio-Italy: A High-Prevalence Region in a Non-Endemic Country |
| المؤلفون: |
Marco Luigetti, Valeria Guglielmino, Giovanni Antonini, Carlo Casali, Marco Ceccanti, Maria Grazia Chiappini, Laura De Giglio, Vincenzo Di Lazzaro, Antonio Di Muzio, Mariangela Goglia, Maurizio Inghilleri, Luca Leonardi, Roberto Massa, Elena Maria Pennisi, Antonio Petrucci, Emanuela Proietti, Marianna Rispoli, Mario Sabatelli, Marco Di Girolamo |
| المصدر: |
Genes; Volume 12; Issue 6; Pages: 829 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2021 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
ATTRv, prevalence, amyloid |
| جغرافية الموضوع: |
agris |
| الوصف: |
Hereditary transthyretin amyloidosis (ATTRv, v for variant) prevalence in Italy, a non-endemic region, has been established by ATTRv amyloidosis Italian Registry. However, values of prevalence were extremely heterogeneous, considering different regions. To properly establish the prevalence of the disease in the Lazio region, a survey was sent to university regional hospitals and to main regional hospitals, in order to collect all affected patients regularly followed. We identified 100 ATTRv patients and, considering a Lazio population of 5.8/million, we estimated a ATTRv prevalence of 17.2/million. The ATTRv amyloidosis Italian Registry reported a prevalence of 8.0/million in Lazio, while our survey showed a value of double this. Our survey documented a high-prevalence for a non-endemic country. The increased awareness of the disease among general practitioners and medical specialists is a fundamental step to reduce the diagnostic delay and start an effective treatment of this disease. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| Relation: |
Molecular Genetics and Genomics; https://dx.doi.org/10.3390/genes12060829 |
| DOI: |
10.3390/genes12060829 |
| الاتاحة: |
https://doi.org/10.3390/genes12060829 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: |
edsbas.3A8CC206 |
| قاعدة البيانات: |
BASE |