Academic Journal
INFLUENCE OF DIFFERENT LIGHTING REGIMEN ON THE MORPHOMETRIC CHARACTERISTICS OF NEURONS IN THE PARAVENTRICULAR NUCLEI OF THE RAT HYPOTHALAMUS ; ВЛИЯНИЕ РАЗНОГО РЕЖИМА ОСВЕЩЕНИЯ НА МОРФОМЕТРИЧЕСКУЮ ХАРАКТЕРИСТИКУ НЕЙРОНОВ ПАРАВЕНТРИКУЛЯРНЫХ ЯДЕР ГИПОТАЛАМУСА КРЫС ; ВПЛИВ РІЗНОГО РЕЖИМУ ОСВІТЛЕННЯ НА МОРФОМЕТРИЧНУ ХАРАКТЕРИСТИКУ НЕЙРОНІВ ПАРАВЕНТРИКУЛЯРНИХ ЯДЕР ГІПОТАЛАМУСА ЩУРІВ
| العنوان: | INFLUENCE OF DIFFERENT LIGHTING REGIMEN ON THE MORPHOMETRIC CHARACTERISTICS OF NEURONS IN THE PARAVENTRICULAR NUCLEI OF THE RAT HYPOTHALAMUS ; ВЛИЯНИЕ РАЗНОГО РЕЖИМА ОСВЕЩЕНИЯ НА МОРФОМЕТРИЧЕСКУЮ ХАРАКТЕРИСТИКУ НЕЙРОНОВ ПАРАВЕНТРИКУЛЯРНЫХ ЯДЕР ГИПОТАЛАМУСА КРЫС ; ВПЛИВ РІЗНОГО РЕЖИМУ ОСВІТЛЕННЯ НА МОРФОМЕТРИЧНУ ХАРАКТЕРИСТИКУ НЕЙРОНІВ ПАРАВЕНТРИКУЛЯРНИХ ЯДЕР ГІПОТАЛАМУСА ЩУРІВ |
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| المؤلفون: | Булик, Р.Є., Сметанюк, О.В., Власова, К.В., Кривчанська, М.І. |
| المصدر: | Клінічна та експериментальна патологія; Том 20 № 3 (2021) ; Клиническая и экспериментальная патология; Том 20 № 3 (2021) ; Clinical & experimental pathology; Vol. 20 No. 3 (2021) ; 1727-4338 |
| بيانات النشر: | Bukovinian State Medical University |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | paraventricular nucleus, morphometric state, light deprivation, constant illumination, паравентрикулярное ядро, морфометрическое состояние, световая депривация, постоянное освещение, паравентрикулярне ядро, морфометричний стан, світлова депривація, постійне освітлення |
| الوصف: | Paraventricular nuclei (PVN) of the hypothalamus are the autonomic center forcoordination of functions and consists of a number of neuronal populations - sub-nuclei,which differ in structural and functional features and the nature of nerve connectionswith various parts of the nervous and neuroendocrine systems. When studying stressreactions and actions of the stress-limiting factors, it is important to study subpopulationsof PVN neurons of the hypothalamus, synthesizing stress-releasing hormones, whichinitiate stress reactions of the body. One of the main factors that show a pronouncedeffect in the regulation of ACTH secretion is corticotropin-releasing factor (CRF). TheCRF-immunoreactive tracer was found mainly in the medial small-cell subnucleus of theparaventricular nuclei of the rat hypothalamus. Despite deep and comprehensive studiesof the hypothalamus, until now there are no unifed ideas about its individual reactivityand the degree of involvement of these structures into the stress reaction caused by theprolonged change in the lighting regime.Purpose - to fnd out the effect of different illumination regimes on the morphometriccharacteristics of the medial small-cell subnuclei of the paraventricular nuclei of thehypothalamus of mature and old rats.Material and methods. The experiments were conducted on 72 nonlinear white malerats, divided into 6 series of studies, in each of which the biomaterial sampling wascarried out at 14.00 and 02.00 h using morphometric and statistical research methods.Results. Morphometric assessment of the medial small-cell sub-nuclei of theparaventricular nuclei (msPVN) of the hypothalamus of rats revealed the diurnaldynamics of indices. It has been established that in both old and mature rats, theiraverage volume (p <0.05) signifcantly decreases at 2.00 compared to 14.00 undernormal lighting. The nuclear-cytoplasmatic ratio at 02.00 increases in comparison with14.00 respectively.When the animals were kept under constant illumination, more pronounced changesin the structures under ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | Ukrainian |
| Relation: | http://cep.bsmu.edu.ua/article/view/245912/243413; http://cep.bsmu.edu.ua/article/view/245912 |
| DOI: | 10.24061/1727-4338.XX.3.77.2021.2 |
| الاتاحة: | http://cep.bsmu.edu.ua/article/view/245912 https://doi.org/10.24061/1727-4338.XX.3.77.2021.2 |
| Rights: | Авторське право (c) 2021 Р.Є. Булик, О.В. Сметанюк, К.В. Власова, М.І. Кривчанська ; http://creativecommons.org/licenses/by-nc-sa/4.0/ |
| رقم الانضمام: | edsbas.3A76BF5C |
| قاعدة البيانات: | BASE |
| DOI: | 10.24061/1727-4338.XX.3.77.2021.2 |
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