Academic Journal
Symptom profile, case and symptom clustering, clinical and demographic characteristics of a multicentre cohort of 1297 patients evaluated for Long-COVID
| العنوان: | Symptom profile, case and symptom clustering, clinical and demographic characteristics of a multicentre cohort of 1297 patients evaluated for Long-COVID |
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| المؤلفون: | Floridia, Marco, Giuliano, Marina, Weimer, Liliana Elena, Ciardi, Maria Rosa, Agostoni, Piergiuseppe, Palange, Paolo, Rovere Querini, Patrizia, Zucco, Silvia, Tosato, Matteo, Lo Forte, Aldo, Bonfanti, Paolo, Lacedonia, Donato, Barisione, Emanuela, Figliozzi, Stefano, Andreozzi, Paola, Damiano, Cecilia, Pricci, Flavia, Onder, Graziano, null, null, Grisetti, Tiziana, Grassi, Tiziana, Tiple, Dorina, Villa, Marika, Polizzi, Cosimo, Galati, Fabio, Pasculli, Patrizia, Colazzo, Francesca, Mattavelli, Irene, Salvioni, Elisabetta, Pellegrino, Daniela, Bezzio, Marco, Olmati, Federica, Sanna, Arianna, Schifano, Arianna, Angelone, Dario, Fabozzi, Antonio, Santoro, Simona, Fumagalli, Anna, Merolla, Aurora, Canti, Valentina, Ruggiero, Maria Pia, Messina, Marco, Biganzoli, Marina, Buonsenso, Danilo, Ianniello, Alice, Galluzzo, Vincenzo, Macculi, Laura, Bottaro, Valeria Maria, Bonaffini, Luca, Spolti, Anna, Squillace, Nicola, Campanino, Terence, Aloè, Teresita, Tagliabue, Elena, Testerini, Federica, Miglionico, Marzia, Barbitta, Antonia, Cenciarelli, Chiara, Pagnanelli, Gianluca, Piccinni, Giuseppe, Gnerre, Paola, Parodi, Lionello, Monaco, Eugenia, Buscaglia, Sandra, Visconti, Antonella, Loso, Kwelusukila, Martino, Giuseppe Pio, Bitti, Giuseppina, Postacchini, Laura, Cognigni, Antonella, di Rosolini, Maria Antonietta, Mavilla, Sergio, Toraldo, Domenico Maurizio, Vagheggini, Guido, Bardi, Giulio, Levantino, Giuseppa, Stefan, Cristina, Parati, Gianfranco, Perger, Elisa, Gianfranceschi, Enrico, Pozzoli, Francesca, De Leo, Pasqualina, Grignolo, Sara, Monari, Caterina, Bianchi, Leila, Galli, Luisa, Surace, Lorenzo, Falbo, Elisabetta, Boni, Silvia, Battello, Claudia, Baghiris, Caterina, Serviddio, Gaetano |
| المساهمون: | Floridia, Marco, Giuliano, Marina, Weimer, Liliana Elena, Ciardi, Maria Rosa, Agostoni, Piergiuseppe, Palange, Paolo, Rovere Querini, Patrizia, Zucco, Silvia, Tosato, Matteo, Lo Forte, Aldo, Bonfanti, Paolo, Lacedonia, Donato, Barisione, Emanuela, Figliozzi, Stefano, Andreozzi, Paola, Damiano, Cecilia, Pricci, Flavia, Onder, Graziano, Null, Null, Grisetti, Tiziana, Grassi, Tiziana, Tiple, Dorina, Villa, Marika, Polizzi, Cosimo, Galati, Fabio, Pasculli, Patrizia, Colazzo, Francesca, Mattavelli, Irene, Salvioni, Elisabetta, Pellegrino, Daniela, Bezzio, Marco, Olmati, Federica, Sanna, Arianna, Schifano, Arianna, Angelone, Dario, Fabozzi, Antonio, Santoro, Simona, Fumagalli, Anna, Merolla, Aurora, Canti, Valentina, Ruggiero, Maria Pia, Messina, Marco, Biganzoli, Marina, Buonsenso, Danilo, Ianniello, Alice, Galluzzo, Vincenzo, Macculi, Laura, Bottaro, Valeria Maria, Bonaffini, Luca, Spolti, Anna, Squillace, Nicola, Campanino, Terence, Aloè, Teresita, Tagliabue, Elena, Testerini, Federica, Miglionico, Marzia, Barbitta, Antonia, Cenciarelli, Chiara, Pagnanelli, Gianluca, Piccinni, Giuseppe, Gnerre, Paola, Parodi, Lionello, Monaco, Eugenia, Buscaglia, Sandra, Visconti, Antonella, Loso, Kwelusukila, Martino, Giuseppe Pio, Bitti, Giuseppina, Postacchini, Laura, Cognigni, Antonella, di Rosolini, Maria Antonietta, Mavilla, Sergio, Toraldo, Domenico Maurizio, Vagheggini, Guido, Bardi, Giulio, Levantino, Giuseppa, Stefan, Cristina, Parati, Gianfranco, Perger, Elisa, Gianfranceschi, Enrico, Pozzoli, Francesca, De Leo, Pasqualina, Grignolo, Sara, Monari, Caterina, Bianchi, Leila, Galli, Luisa, Surace, Lorenzo, Falbo, Elisabetta, Boni, Silvia, Battello, Claudia, Baghiris, Caterina, Serviddio, Gaetano |
| سنة النشر: | 2024 |
| المجموعة: | Università degli Studi di Foggia: CINECA IRIS Institutional Research Information System |
| مصطلحات موضوعية: | COVID-19, Dyspnea, Fatigue, Long-COVID, Post-COVID, Symptom cluster, Symptoms |
| الوصف: | Background: Long-COVID symptoms remain incompletely defined due to a large heterogeneity in the populations studied, case definitions, and settings of care. The aim of this study was to assess, in patients accessing care for Long-COVID, the profile of symptoms reported, the possible clustering of symptoms and cases, the functional status compared to pre-infection, and the impact on working activity. Methods: Multicentre cohort study with a collection of both retrospective and prospective data. Demographics, comorbidities, severity and timing of acute COVID, subjective functional status, working activity and presence of 30 different symptoms were collected using a shortened version of the WHO Post COVID-19 Case Report Form. The impact on working activity was assessed in multivariable logistic regression models. Clustering of symptoms was analysed by hierarchical clustering and the clustering of cases by two-step automatic clustering. Results: The study evaluated 1297 individuals (51.5% women) from 30 clinical centres. Men and women had different profiles in terms of comorbidities, vaccination status, severity and timing of acute SARS-CoV-2 infection. Fatigue (55.9%) and dyspnea (47.2%) were the most frequent symptoms. Women reported more symptoms (3.6 vs. 3.1, p < 0.001), with a significantly higher prevalence of memory loss, difficult concentration, cough, palpitation or tachycardia, dermatological abnormalities, brain fog, headache and visual disturbances. Dyspnea was more common in men. In the cluster analysis of the 19 more common symptoms, five aggregations were found: four two-symptom clusters (smell and taste reduction; anxiety and depressed mood; joint pain or swelling and muscle pain; difficult concentration and memory loss) and one six-symptom cluster (brain fog, equilibrium/gait disturbances, headache, paresthesia, thoracic pain, and palpitations/tachycardia). In a multivariable analysis, headache, dyspnea, difficult concentration, disturbances of equilibrium or gait, visual disturbances and ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/39543596; info:eu-repo/semantics/altIdentifier/wos/WOS:001355579800002; volume:22; issue:1; journal:BMC MEDICINE; https://hdl.handle.net/11369/463673 |
| DOI: | 10.1186/s12916-024-03746-9 |
| الاتاحة: | https://hdl.handle.net/11369/463673 https://doi.org/10.1186/s12916-024-03746-9 |
| رقم الانضمام: | edsbas.3A48F9C6 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/s12916-024-03746-9 |
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