Academic Journal

Phosphotyrosine phosphatase R3 receptors: Origin, evolution and structural diversification

التفاصيل البيبلوغرافية
العنوان: Phosphotyrosine phosphatase R3 receptors: Origin, evolution and structural diversification
المؤلفون: Garcia-España, A, Chicote, J.U., DeSalle, R.
المساهمون: Grup de Recerca Biomèdica HJ23, Bioquímica i Biotecnologia, Universitat Rovira i Virgili
المصدر: Plos One ; https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0172887 ; https://doi.org/10.1371/journal.pone.0172887
سنة النشر: 2017
المجموعة: Universitat Rovira i Virgili: Repositori institucional URV
مصطلحات موضوعية: Proteïna-tirosina-fosfatasa, Està en blanc, Biochemistry and technology, Bioquímica y tecnología, Bioquímica i biotecnologia
جغرافية الموضوع: Anglès
Time: 1932-6203
الوصف: Limited data exists on the interrelationships between physical activity (PA), sedentary behaviors and sleep concerning cardiometabolic risk factors in aged adults at high cardiovascular disease risk. Our aim was to examine independent and joint associations between time spent in leisure-time PA, sedentary behaviors and sleep on the prevalence of obesity, type 2 diabetes (T2D) and components of the metabolic syndrome (MetS) in Mediterranean individuals at high cardiovascular risk. Cross-sectional analyses were performed on baseline data from 5776 Spanish adults (aged 55-75y in men; 60-75y in women) with overweight/ obesity and MetS, from October 2013 to October 2016, in the PREDIMED-PLUS trial. Employing multivariable-adjusted Cox regression with robust variance and constant time (given the cross-sectional design), higher prevalence of obesity, T2D and abdominal obesity as component of the MetS were associated with greater time in TV-viewing (Relative Risk, RR: 1.02, 95%CI: 1.01, 1.03; RR:1.04, 95%CI: 1.02, 1.06 and RR: 1.01 95%CI: 1.00, 1.02; respectively, all P < .01). Conversely, greater time in moderate-vigorous PA (MVPA) was associated with lower prevalence of obesity, T2D, abdominal obesity and low HDL-cholesterol (RR: 0.95, 95%CI: 0.93, 0.97; RR: 0.94, 95%CI: 0.89, 0.99; RR: 0.97, 95%CI: 0.96, 0.98; and RR: 0.95, 95%CI: 0.91, 0.99, respectively, all P < .05). For these outcomes, theoretically substituting 1-h/day of MVPA for 1-h/day TV-viewing was also significantly associated with lower prevalence (RR 0.91 to 0.97, all P < .05). Similar lower RR in these outcomes was observed when substituting 1-h/day of MVPA for 1-h/day of sleeping. Longer time watching TV and not meeting MVPA recommendations were jointly associated with higher RR of the prevalence of o
نوع الوثيقة: article in journal/newspaper
وصف الملف: 1871 kb
اللغة: unknown
Relation: http://hdl.handle.net/20.500.11797/PC2677
الاتاحة: https://hdl.handle.net/20.500.11797/PC2677
Rights: openAccess
رقم الانضمام: edsbas.3A3A96E6
قاعدة البيانات: BASE