Academic Journal
Sister Mary Joseph's nodule: report of five cases
| العنوان: | Sister Mary Joseph's nodule: report of five cases |
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| المؤلفون: | Masmoudi, Abderrahmen, Boudaya, Sonia, Charfeddine, Amel, Dammak, Anis, Amouri, Mariem, Khabir, Abdelmajid, Marrekchi, Sleheddine, Bouassida, Samir, Sallemi, Tahia, Krichen, Mohamed Salah, Turki, Hamida, Zahaf, Abdelmajid |
| المصدر: | International Journal of Dermatology ; volume 47, issue 2, page 134-136 ; ISSN 0011-9059 1365-4632 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2008 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Case 1 A 54‐year‐old woman presented with a 5‐month history of an asymptomatic, 2.5‐cm, erythematous, ulcerated nodule involving the umbilicus ( Fig. 1 ). Biopsy demonstrated metastatic adenocarcinoma ( Fig. 2 ) and abdominal ultrasound showed a large ovarian tumor ( Table 1 ). Further evaluation revealed pleural metastases. Erythematous nodule of the umbilicus image Proliferation of glandular structures composed of tumor cells with prominent nucleoli and numerous mitoses (hematoxylin and eosin, ×4000) image Primary malignancy in five patients with Sister Mary Joseph's nodule Case Age (years) Gender Primary malignancy 1 54 Female Ovarian adenocarcinoma 2 58 Male Colorectal adenocarcinoma 3 42 Male Pancreatic adenocarcinoma 4 58 Male Ileocecal sarcoma 5 58 Female Cholangiocarcinoma Case 2 A 58‐year‐old man was hospitalized with a 6‐month history of diffuse abdominal pain, a 2‐week history of a cutaneous nodule, and a 5‐day history of bloody diarrhea. Cutaneous examination revealed a 1.5‐cm, erythematous to violaceous, infiltrative, and verrucous nodule of the umbilicus ( Fig. 3 ). Colonoscopy showed a pedunculated polyp of the right colon and a loss of substance in the anal area; histologic examination demonstrated well‐differentiated adenocarcinoma. Abdominal ultrasound showed moderate ascites. A diagnosis of colorectal adenocarcinoma ( Table 1 ) with umbilical metastasis and peritoneal carcinomatosis was made. Irregular, infiltrative, verrucous nodule of the umbilicus image Case 3 A 42‐year‐old man, with a history of surgery 5 months earlier for a perforated gastric ulcer, was hospitalized with a 2‐month history of abdominal pain and general deterioration. Clinical examination showed a 15‐cm infiltrative area at the central abdomen with coalescing ulcerated papules at the umbilicus ( Fig. 4 ), which developed during the onset of abdominal pain. Histologic evaluation revealed metastatic adenocarcinoma to the skin. Further evaluation supported a diagnosis of pancreatic cancer with peritoneal carcinomatosis ( ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1111/j.1365-4632.2008.03434.x |
| الاتاحة: | http://dx.doi.org/10.1111/j.1365-4632.2008.03434.x https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-4632.2008.03434.x https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-4632.2008.03434.x |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.3A1C622E |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/j.1365-4632.2008.03434.x |
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