Academic Journal
Fatal tuberculosis in a free-ranging African elephant and one health implications of human pathogens in wildlife
| العنوان: | Fatal tuberculosis in a free-ranging African elephant and one health implications of human pathogens in wildlife |
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| المؤلفون: | Miller, Michele A., Buss, Peter Erik, Roos, Eduard O., Hausler, Guy, Dippenaar, Anzaan, Mitchell, Emily P., Van Schalkwyk, Louis, Robbe-Austerman, Suelee, Waters, W. Ray, Sikar-Gang, Alina, Lyashchenko, Konstantin P., Parsons, Sven D.C., Warren, Robin, Van Helden, Paul David |
| بيانات النشر: | Frontiers Media |
| سنة النشر: | 2019 |
| المجموعة: | University of Pretoria: UPSpace |
| مصطلحات موضوعية: | Anthroponosis, One health, Wildlife disease, African elephant (Loxodonta africana), Mycobacterium tuberculosis (MTB), Tuberculosis (TB), Veterinary science articles SDG-03, Veterinary science articles SDG-15, SDG-15: Life on land, SDG-03: Good health and well-being |
| الوصف: | Tuberculosis (TB) in humans is a global public health concern and the discovery of animal cases of Mycobacterium tuberculosis (Mtb) infection and disease, especially in multi-host settings, also has significant implications for public health, veterinary disease control, and conservation endeavors. This paper describes a fatal case of Mtb disease in a free-ranging African elephant (Loxodonta africana) in a high human TB burden region. Necropsy revealed extensive granulomatous pneumonia, from which Mtb was isolated and identified as a member of LAM3/F11 lineage; a common lineage found in humans in South Africa. These findings are contextualized within a framework of emerging Mtb disease in wildlife globally and highlights the importance of the One Health paradigm in addressing this anthroponotic threat to wildlife and the zoonotic implications. ; The South African Medical Research Council and National Research Foundation, including the South African Research Chair Initiative (grant number 86949); and by National Research Foundation core funding given to the National Zoological Gardens. ; https://www.frontiersin.org/journals/veterinary-science# ; am2019 ; Veterinary Tropical Diseases |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | 2297-1769 (online); http://hdl.handle.net/2263/71263 |
| DOI: | 10.3389/fvets.2019.00018 |
| الاتاحة: | http://hdl.handle.net/2263/71263 https://doi.org/10.3389/fvets.2019.00018 |
| Rights: | © 2019 Miller, Buss, Roos, Hausler, Dippenaar, Mitchell, van Schalkwyk, Robbe-Austerman, Waters, Sikar-Gang, Lyashchenko, Parsons, Warren and van Helden. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). |
| رقم الانضمام: | edsbas.39D9DA61 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3389/fvets.2019.00018 |
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