Academic Journal
Five-Years Tigecycline Experience an Analysis of Real-Life Data
| العنوان: | Five-Years Tigecycline Experience an Analysis of Real-Life Data |
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| المؤلفون: | Fatih Temocin, Necla Eren Tülek, Şirin Hekimoğlu, Tuba Ilgar, Cemal Bulut, Fatma Şebnem Erdinç, Günay Tuncer Ertem, Çiğdem Ataman Hatipoğlu, Sami Kınıklı |
| المصدر: | Haseki Tıp Bülteni, Vol 56, Iss 2, Pp 125-130 (2018) |
| بيانات النشر: | Galenos Yayinevi |
| سنة النشر: | 2018 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Tigecycline, real life data, minocycline, Medicine, Medicine (General), R5-920 |
| الوصف: | Aim: Tigecycline has been approved by the Food and Drug Administration for the treatment of complicated intra-abdominal infections, skin and soft tissue infections and community-acquired pneumonia. In our study, we examined the efficacy of tigecycline in clinical practice and reported real life data from our hospital over a period of five years. Methods: The study was conducted between 2008 and 2013 on patients who received tigecycline for longer than 48 hours in Ankara Training and Research Hospital. Clinical success was defined as clinical recovery and microbiological cure in patients who used tigecycline. Any reason for discontinuation of tigecycline treatment was considered a clinical failure. Results: In our hospital, 320 patients were administered tigecycline between 2008 and 2013. Tigecycline was mainly used for pneumonia and skin and soft tissue infections. Tigecycline was used as monotherapy in 174 patients (54.1%). The most frequently isolated agent in tigecycline-treated patients was Acinetobacter baumannii (43.4%) followed by Enterococcus (6.9%). A change in treatment was not considered necessary in 243 (75.9%) patients who received tigecycline, while it was changed in 77 patients (24.1%). Conclusion: In conclusion, the use of tigecycline can be an effective treatment choice, either as monotherapy or as a combination antibiotic therapy. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English Turkish |
| تدمد: | 1302-0072 2147-2688 |
| Relation: | http://www.hasekidergisi.com/archives/archive-detail/article-preview/five-years-tigecycline-experience-an-analysis-of-r/19005; https://doaj.org/toc/1302-0072; https://doaj.org/toc/2147-2688; https://doaj.org/article/297928a1881144eb95a2eebc2503df9a |
| DOI: | 10.4274/haseki.42713 |
| الاتاحة: | https://doi.org/10.4274/haseki.42713 https://doaj.org/article/297928a1881144eb95a2eebc2503df9a |
| رقم الانضمام: | edsbas.38F8C7CD |
| قاعدة البيانات: | BASE |
| تدمد: | 13020072 21472688 |
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| DOI: | 10.4274/haseki.42713 |