Academic Journal
Diagnostic Certainty in Characterizing Liver Lesions in Rectal Cancer: Abbreviated Liver MRI versus CT
| العنوان: | Diagnostic Certainty in Characterizing Liver Lesions in Rectal Cancer: Abbreviated Liver MRI versus CT |
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| المؤلفون: | Wale, Anita, Harris, Heather, Brown, Gina |
| المساهمون: | Pelican Cancer Foundation, National Institute Health Research, Biomedical Research Centre at Royal Marsden Hospital and Imperial College London, Bowel Research UK, Imperial College London |
| المصدر: | Annals of Surgical Oncology ; ISSN 1068-9265 1534-4681 |
| بيانات النشر: | Springer Science and Business Media LLC |
| سنة النشر: | 2025 |
| الوصف: | Background Early diagnosis of metastases is crucial but routine staging with contrast-enhanced multidetector computed tomography (ceMDCT) is suboptimal. A total of 20% will have indeterminate or too small to characterize (TSTC) liver lesions on CT, requiring formal characterization by magnetic resonance imaging (MRI). This UK cross-sectional study reports our experience undertaking routine abbreviated liver MRI (MRI). Patients and Methods A total of 99 patients with rectal cancer had ceMDCT, abbreviated liver MRI, and rectal MRI at diagnosis. Liver imaging was scored for liver metastases, benign or indeterminate/TSTC lesions on a per patient basis. Primary rectal cancer was risk scored on MRI. Results A total of 42/99 (42%) had liver lesion(s) on ceMDCT versus 55/99 (56%) by MRI, and 46/99 (46%) had high-risk rectal cancer. ceMDCT showed 5 patients with liver metastases, 14 with benign lesions, and 23 with indeterminate/TSTC lesions. MRI showed 6 with liver metastases, 45 with benign lesions, and 4 with indeterminate/TSTC lesions. All liver metastases were in high-risk rectal cancer, OR 17.18 ( p = 0.06), with 12.5% conversion rate of TSTC lesions to metastases in high-risk rectal cancer and 0% in low-risk rectal cancer. Diagnostic certainty of the liver findings was achieved in 93% of patients by MRI compared with 45% by ceMDCT ( p < 0.0001). Discussion Abbreviated liver MRI diagnosed fewer indeterminate/TSTC lesions and provided greater diagnostic certainty than ceMDCT, p < 0.0001. High-risk rectal cancer is associated with a higher conversation rate of TSTC lesions to metastases than low-risk rectal cancers. Risk stratified; routine abbreviated liver MRI sequences should be investigated as part of the patient pathway for high-risk rectal cancer. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1245/s10434-024-16468-2 |
| DOI: | 10.1245/s10434-024-16468-2.pdf |
| DOI: | 10.1245/s10434-024-16468-2/fulltext.html |
| الاتاحة: | https://doi.org/10.1245/s10434-024-16468-2 https://link.springer.com/content/pdf/10.1245/s10434-024-16468-2.pdf https://link.springer.com/article/10.1245/s10434-024-16468-2/fulltext.html |
| Rights: | https://creativecommons.org/licenses/by/4.0 ; https://creativecommons.org/licenses/by/4.0 |
| رقم الانضمام: | edsbas.387C18F2 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1245/s10434-024-16468-2 |
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