التفاصيل البيبلوغرافية
| العنوان: |
COVID-19 in celiac disease: a multicentric retrospective cohort study |
| المؤلفون: |
G. Gasbarrini, T. Dionisi, G.R. Corazza, N. Aronico, G. Cammarota, G. Ianiro, I. De Vitis, M. Candelli, F.A. Mancarella, S. Simeoni, G. Addolorato, F. Bonvicini |
| المصدر: |
European Review for Medical and Pharmacological Sciences, Vol 25 (2021) |
| بيانات النشر: |
Verduci Editore |
| سنة النشر: |
2021 |
| المجموعة: |
Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: |
Therapeutics. Pharmacology, RM1-950 |
| الوصف: |
OBJECTIVE: Celiac disease (CD) is an autoimmune disorder, characterized by increased susceptibility to bacterial and viral infections. Therefore, the CD patients could be exposed to an increased risk of contracting SARS-CoV-2, a virus for which the WHO declared a pandemic status in March 2020. This study aims to investigate the incidence of SARS-CoV-2 infection in CD patients, to assess the impact of CD on the risk of contracting this virus. PATIENTS AND METHODS: This retrospective multicentric cohort study evaluated 542 celiac patients, who answered a questionnaire concerning both the underlying disease (adherence to the gluten-free diet, residual symptoms) and the possible SARS-CoV-2 infection (swab outcome, presence and characteristics of symptoms and type of treatment received), referring to the period between 20th January 2020 and 27th October 2020. RESULTS: Five patients (0.92%) tested positive; of these, 2 were asymptomatic and 3 developed symptoms of COVID-19. The incidence of SARS-CoV-2 infection in CD patients was not significantly different from the general population. The ratio of positive/diagnostic swabs tends to be higher in CD patients than in the general population (IR: 0.15; 0.06; p=0.06), whereas the number of subjects who performed the swab in this group is significantly lower (IR: 0.06; 0.15; p<0.001). CONCLUSIONS: Although CD patients are more susceptible to infections, the incidence of SARS-CoV-2 infection in our sample was not significantly different from the general population. However, the positive/diagnostic swabs ratio seems to be higher, probably also due to the lower number of patients tested. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| تدمد: |
1128-3602 |
| Relation: |
https://www.europeanreview.org/wp/wp-content/uploads/4400-4404.pdf; https://doaj.org/toc/1128-3602; https://doaj.org/article/3ad2ab1b229c40a2bd6a752fb0b33250 |
| الاتاحة: |
https://doaj.org/article/3ad2ab1b229c40a2bd6a752fb0b33250 |
| رقم الانضمام: |
edsbas.3876DF66 |
| قاعدة البيانات: |
BASE |