Academic Journal
Increased Proportion of Comorbidities but no Deterioration of sexual QOL during a 5-year follow-up in Patients with ax-SpA in the biologic Treatment Era
| العنوان: | Increased Proportion of Comorbidities but no Deterioration of sexual QOL during a 5-year follow-up in Patients with ax-SpA in the biologic Treatment Era |
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| المؤلفون: | Berg, Kari Hansen, Rohde, Gudrun Elin, Pripp, Are Hugo, Prøven, Anne, Benestad, Espen Esther Pirelli, Østensen, Monika Elisabeth, Haugeberg, Glenn |
| المصدر: | 4112-4120 ; 60 ; Rheumatology ; 9 |
| بيانات النشر: | Oxford University Press |
| سنة النشر: | 2021 |
| المجموعة: | Universitetet i Agder: Open Archive (AURA) |
| مصطلحات موضوعية: | VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Reumatologi: 759 |
| الوصف: | Author's accepted manuscript. ; This is a pre-copyedited, author-produced version of an article accepted for publication in Rheumatology following peer review. The version of record Berg, K. H., Rohde, G., Pripp, A., Prøven, A., Benestad, E. E. P., Østensen, M. & Haugeberg, G. (2021). Increased proportion of comorbidities but no deterioration of sexual QOL during a 5-year follow-up in patients with axSpA in the biologic treatment era. Rheumatology, 60(9), 4112-4120 is available online at: https://academic.oup.com/rheumatology/article/60/9/4112/6067306 and https://doi.org/10.1093/rheumatology/keaa887. ; Objective. To explore patient perception of sexual quality of life (SQOL), an important category of QOL, in male and female patients with axial SpA (axSpA) after a 5 year follow-up. Methods. A broad spectrum of demographic, disease-related, treatment and SQOL data was collected at baseline and at the 5 year follow-up. SQOL was assessed by the SQOL-Female (SQOL-F) questionnaire. For statistical analysis, McNemar’s tests, paired t-tests and multiple regression analyses were applied. Results. A total of 245 axSpA patients (168 men and 77 women) from outpatient clinics were examined (mean age 46 years, mean disease duration 11.9 years at baseline). Compared with baseline, the patients had lower CRP, lower Maastricht Ankylosing Spondylitis Enthesitis Scores, lower BASFI scores, less use of smoking and significantly more patients were treated with biologic DMARDs at the 5 year follow-up. Patient perception of SQOL was basically unchanged at the 5 year follow-up despite a significantly increased proportion of comorbidities, including cardiovascular, endocrine and gastrointestinal disease. A decrease in SQOL after 5 years was observed only in patients exercising <1 h/week at baseline (P ¼ 0.048) and in patients >65 years old. Conclusion. In our axSpA patients, no statistically significant changes in SQOL were observed over 5 years, despite a significant increase in comorbidities. Overall disease symptoms ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1462-0332 |
| Relation: | Berg, K. H., Rohde, G., Pripp, A., Prøven, A., Benestad, E. E. P., Østensen, M. & Haugeberg, G. (2021). Increased proportion of comorbidities but no deterioration of sexual QOL during a 5-year follow-up in patients with axSpA in the biologic treatment era. Rheumatology, 60(9), 4112-4120.; urn:issn:1462-0332; https://hdl.handle.net/11250/3043407; https://doi.org/10.1093/rheumatology/keaa887; cristin:1848190 |
| DOI: | 10.1093/rheumatology/keaa887 |
| الاتاحة: | https://hdl.handle.net/11250/3043407 https://doi.org/10.1093/rheumatology/keaa887 |
| Rights: | © 2021 The Author(s) |
| رقم الانضمام: | edsbas.38766071 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 14620332 |
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| DOI: | 10.1093/rheumatology/keaa887 |