Academic Journal
Effectiveness Combination of Ginger Extract (Zingiber officinale) and Ranitidine Compared with Combination of Ranitidine and Placebo against Severity of Functional Dyspepsia
| العنوان: | Effectiveness Combination of Ginger Extract (Zingiber officinale) and Ranitidine Compared with Combination of Ranitidine and Placebo against Severity of Functional Dyspepsia |
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| المؤلفون: | Prapti, Dite Ari, Ratnasari, Neneng, Nurdjanah, Siti |
| المصدر: | Acta Interna: The Journal of Internal Medicine; Vol 7, No 1 (2017): Acta Interna The Journal of Internal Medicine; 47-54 ; Acta Interna The Journal of Internal Medicine; Vol 7, No 1 (2017): Acta Interna The Journal of Internal Medicine; 47-54 ; 2541-5441 ; 2303-131X |
| بيانات النشر: | Faculty of Medicine Universitas Gadjah Mada |
| سنة النشر: | 2019 |
| المجموعة: | Universitas Gadjah Mada Online Journals |
| مصطلحات موضوعية: | ABSTRACT Background: Efficacy ranitidine as dyspepsia functional treatment was 8-35 % and ginger extracts as a traditional recipe in various countries for generations could be used as a therapy dyspepsia, antinausea, spasm, colic, and other stomach compla |
| الوصف: | Background: Efficacy ranitidine as dyspepsia functional treatment was 8-35 % and ginger extracts as a traditional recipe in various countries for generations could be used as a therapy dyspepsia, antinausea, spasm, colic, and other stomach complaints. Ginger therapeutic effectiveness could reach 68-77% in vivo studies (animal models).Objective: To determined how much influence combination of ginger extract and ranitidine could improve severity of dyspepsia compared with combination of ranitidine and placebo in patients with functional dyspepsia.Method: This study was a quasi experimental. The research was conducted from December 2015 until April 2016 with 26 participants.Results: After getting therapy for 2 weeks in group I, mean SODA score in the pain scale decreased (8.4 %) of 29.07 ± 7.29 to 25.08 ± 8.22, statistically significant (p <0.046). Mean SODA score in the pain scale group II decreased (7.2%) of 25.38 ± 6.19 to 24 ± 6.01 (p=0.302). Mean SODA score in the non pain scale in group I decreased (7.7%) of 16.84 ± 2.44 to 15.15 ± 2.64 (p=0.074), while in the group II decreased (1.6%) of 15.77 ± 2.71 to 15.23 ± 2.94 (p=0.470). Mean SODA score in the satisfaction scale in group I increased (19.9%) of 7.77 ± 3.63 to 10.08 ± 3.59 (p=0.053) while in the group II increased (8.4%) of 9.62 ± 2.72 to 10.92 ± 2.46 (p=0.072). Comparison decline of SODA score in the pain scale between group I was 4.31 ± 6.3 and in group II is 1.23 ± 4.91, greater in group I but not significantly (p=0.178) at baseline to week 2nd. Comparison decline of SODA score in the non pain scale between group I was 1.69 ± 3.11 and in group II was 0.54 ± 2.6, greater in group I but not significantly (p=0.316) at baseline to week 2nd. Comparison increasing of SODA score in the satisfaction scale between group I was – 2.31 ± 3.88 and in group II was -1.31 ± 2.39, greater in group I but not significantly (p=0.437). Conclusion: Combination of ginger extract and ranitidine could decrease pain scale, non pain scale and increase satisfaction ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | https://jurnal.ugm.ac.id/jain/article/view/48406/25092; https://jurnal.ugm.ac.id/jain/article/view/48406 |
| DOI: | 10.22146/actainterna.48406 |
| الاتاحة: | https://jurnal.ugm.ac.id/jain/article/view/48406 https://doi.org/10.22146/actainterna.48406 |
| Rights: | Copyright (c) 2019 Acta Interna: The Journal of Internal Medicine ; http://creativecommons.org/licenses/by-sa/4.0 |
| رقم الانضمام: | edsbas.3861955C |
| قاعدة البيانات: | BASE |
| DOI: | 10.22146/actainterna.48406 |
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