Academic Journal
Association of immediate versus delayed extubation of patients admitted to intensive care units postoperatively and outcomes: A retrospective study
العنوان: | Association of immediate versus delayed extubation of patients admitted to intensive care units postoperatively and outcomes: A retrospective study |
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المؤلفون: | Zajic, Paul, Eichinger, Michael, Eichlseder, Michael, Hallmann, Barbara, Honnef, Gabriel, Fellinger, Tobias, Metnitz, Barbara, Posch, Martin, Rief, Martin, Metnitz, Philipp G. H. |
المساهمون: | Cortegiani, Andrea |
المصدر: | PLOS ONE ; volume 18, issue 1, page e0280820 ; ISSN 1932-6203 |
بيانات النشر: | Public Library of Science (PLoS) |
سنة النشر: | 2023 |
المجموعة: | PLOS Publications (via CrossRef) |
الوصف: | Aim of this study This study seeks to investigate, whether extubation of tracheally intubated patients admitted to intensive care units (ICU) postoperatively either immediately at the day of admission (day 1) or delayed at the first postoperative day (day 2) is associated with differences in outcomes. Materials and methods We performed a retrospective analysis of data from an Austrian ICU registry. Adult patients admitted between January 1 st , 2012 and December 31 st , 2019 following elective and emergency surgery, who were intubated at the day 1 and were extubated at day 1 or day 2, were included. We performed logistic regression analyses for in-hospital mortality and over-sedation or agitation following extubation. Results 52 982 patients constituted the main study population. 1 231 (3.3%) patients extubated at day 1 and 958 (5.9%) at day 2 died in hospital, 464 (1.3%) patients extubated at day 1 and 613 (3.8%) at day 2 demonstrated agitation or over-sedation after extubation during ICU stay; OR (95% CI) for in-hospital mortality were OR 1.17 (1.01–1.35, p = 0.031) and OR 2.15 (1.75–2.65, p<0.001) for agitation or over-sedation. Conclusions We conclude that immediate extubation as soon as deemed feasible by clinicians is associated with favourable outcomes and may thus be considered preferable in tracheally intubated patients admitted to ICU postoperatively. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
DOI: | 10.1371/journal.pone.0280820 |
الاتاحة: | http://dx.doi.org/10.1371/journal.pone.0280820 https://dx.plos.org/10.1371/journal.pone.0280820 |
Rights: | http://creativecommons.org/licenses/by/4.0/ |
رقم الانضمام: | edsbas.385CED4 |
قاعدة البيانات: | BASE |
DOI: | 10.1371/journal.pone.0280820 |
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