التفاصيل البيبلوغرافية
| العنوان: |
Late incidence and recurrence of new-onset atrial fibrillation after isolated surgical aortic valve replacement |
| المؤلفون: |
Björn, R. (Rikhard), Nissinen, M. (Maunu), Lehto, J. (Joonas), Malmberg, M. (Markus), Yannopoulos, F. (Fredrik), Airaksinen, K. E. (K. E. Juhani), Hartikainen, J. E. (Juha E. K.), Nieminen, T. (Tuomo), Biancari, F. (Fausto), Gunn, J. (Jarmo), Kiviniemi, T. O. (Tuomas O.) |
| بيانات النشر: |
Elsevier |
| سنة النشر: |
2022 |
| المجموعة: |
Jultika - University of Oulu repository / Oulun yliopiston julkaisuarkisto |
| مصطلحات موضوعية: |
new-onset atrial fibrillation, surgical aortic valve replacement |
| الوصف: |
Objectives: Atrial fibrillation (AF) is a common complication after cardiac surgery. More knowledge is needed about long-term AF recurrence and adverse outcomes related to new-onset AF (NOAF) during the index hospitalization. Methods: A total of 1073 patients underwent isolated surgical aortic valve replacement at the 4 participating hospitals (2002–2014). After the exclusion of patients with a history of any preoperative AF, the final study population included 529 patients in the bioprosthetic and 253 patients in the mechanical valve prosthesis cohort. Median follow-up time was 5.4 (interquartile range, 3.4–8.2) years in the combined cohort. Results: Altogether 333 (42.6%) patients had in-hospital NOAF and 250 (32.0%) AF after hospital discharge. In the mechanical cohort, 64 (25.3%) experienced in-hospital NOAF and 74 (29.2%) AF after hospital discharge, whereas in the bioprosthetic cohort, 269 (50.9%) patients had in-hospital NOAF and 176 (33.3%) AF after hospital discharge. Patients with NOAF during the index hospital stay had a multifold risk of AF after hospital discharge in the combined cohort (hazard ratio [HR], 3.68; 95% confidence interval [CI], 2.82-4.81; P < .0001) as well as in both cohorts separately (bioprosthetic: HR, 4.35; 95% CI, 3.05-6.22; P < .001; mechanical: HR, 2.54; 95% CI, 1.59-4.03; P < .001). Patients with an in-hospital NOAF also had a significantly higher adjusted risk of death during the follow-up in the mechanical (HR, 2.05; 95% CI, 1.10-3.82; P = .025) and bioprosthetic (HR, 1.63; 95% CI, 1.17-2.28; P = .004) valve prosthesis cohorts. Conclusions: NOAF during the index hospitalization is associated with a 2- to 4-fold risk of later AF and 1.6- to 2.0-fold risk of all-cause mortality after mechanical and bioprosthetic surgical aortic valve replacement. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| الاتاحة: |
http://urn.fi/urn:nbn:fi-fe2023070790439 |
| Rights: |
info:eu-repo/semantics/openAccess ; © 2021 The Authors. Published by Elsevier Inc. on behalf of The American Association for Pediatric Ophthalmology and Strabismus. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). ; https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: |
edsbas.3819CD10 |
| قاعدة البيانات: |
BASE |