التفاصيل البيبلوغرافية
| العنوان: |
Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways |
| المؤلفون: |
Gómez González, Belén, Klein, Hannah L., Chebal, Anais, Che, Jun, Bačinskaja, Giedrė |
| المساهمون: |
Universidad de Sevilla. Departamento de Genética |
| بيانات النشر: |
Shared Science Publishers |
| سنة النشر: |
2019 |
| المجموعة: |
idUS - Deposito de Investigación Universidad de Sevilla |
| مصطلحات موضوعية: |
DNA breaks, Holliday junctions, DNA repair centers, DNA resection, DSBs, gene amplification, gene conversion, genome instability, gross chromosome rearrangements |
| الوصف: |
Understanding the plasticity of genomes has been greatly aided by assays for recombination, repair and mutagenesis. These assays have been developed in microbial systems that provide the advantages of genetic and molecular reporters that can readily be manipulated. Cellular assays comprise genetic, molecular, and cytological reporters. The assays are powerful tools but each comes with its particular advantages and limitations. Here the most commonly used assays are reviewed, discussed, and presented as the guidelines for future studies. ; España , MINECO BFU2016-75058-P ; España, Junta de Andalucía BIO1238 ; European research Council (ERC2014- ADG669898 TARLOOP) ; NIH grant R01-CA146940. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| Relation: |
Microbial Cell, 6 (1), 1-64.; BIO1238; BFU2016-75058-P; ERC2014- ADG669898 TARLOOP; R01-CA146940; http://dx.doi.org/10.15698/mic2019.01.664 |
| الاتاحة: |
https://idus.us.es/xmlui/handle//11441/85678 |
| Rights: |
Attribution-NonCommercial-NoDerivatives 4.0 Internacional ; http://creativecommons.org/licenses/by-nc-nd/4.0/ ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: |
edsbas.3811EDA7 |
| قاعدة البيانات: |
BASE |