Academic Journal
An Adherence-Enhancing Program Increases Retention in Care in the Swiss HIV Cohort.
| العنوان: | An Adherence-Enhancing Program Increases Retention in Care in the Swiss HIV Cohort. |
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| المؤلفون: | Kamal, S., Glass, T.R., Doco-Lecompte, T., Locher, S., Bugnon, O., Parienti, J.J., Cavassini, M., Schneider, M.P. |
| المصدر: | Open forum infectious diseases, vol. 7, no. 9, pp. ofaa323 |
| سنة النشر: | 2020 |
| المجموعة: | Université de Lausanne (UNIL): Serval - Serveur académique lausannois |
| مصطلحات موضوعية: | HIV, adherence intervention, antiretrovirals, interprofessionality, medication retention in care |
| الوصف: | This study tested a theory-based adherence-enhancing intervention: the "Interprofessional Medication Adherence Program" (IMAP) to increase human immunodeficiency virus (HIV) retention in care. We retrospectively compared our intervention center (intervention group [IG]) with a standard of care center (control group [CG]) both participating in the Swiss HIV Cohort Study between 2004 and 2012. Endpoints were defined as >6-month and >12-month gaps in care for intervals of care longer than 6 and 12 months without any blood draw. Inverse probability of treatment weights was used to adjust for differences between patients at the 2 centers. Viral failure was defined as ribonucleic acid ≥50 copies/mL after 24+ weeks on antiretrovirals. The IG included 451 patients, CG 311. In the IG, 179 (40%) patients took part in the IMAP for a median of 27 months (interquartile range, 12-45). Gaps in care of ≥6 months were significantly more likely to happen in the CG versus IG (74.6% vs 57%, P < .001). The median time until the first treatment gap was longer in the IG vs CG (120 vs 84 weeks, P < .001). Gaps in care of ≥12 months evaluated in 709 (93%) patients were significantly more likely to occur in the CG compared with the IG (22.6% vs 12.5%, P < .001). The rate of viral failure was significantly lower in the IG (8.3% vs 15.1%, P = .003). This study, in a real-world setting, shows the effectiveness of the IMAP to reduce 6- and 12-month gaps in follow up among people with HIV. These results should be confirmed by studies in other settings. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/32913876; info:eu-repo/semantics/altIdentifier/pissn/2328-8957; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_FAEE71EBE3B08; https://serval.unil.ch/notice/serval:BIB_FAEE71EBE3B0; https://serval.unil.ch/resource/serval:BIB_FAEE71EBE3B0.P001/REF.pdf |
| DOI: | 10.1093/ofid/ofaa323 |
| الاتاحة: | https://serval.unil.ch/notice/serval:BIB_FAEE71EBE3B0 https://doi.org/10.1093/ofid/ofaa323 https://serval.unil.ch/resource/serval:BIB_FAEE71EBE3B0.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_FAEE71EBE3B08 |
| Rights: | info:eu-repo/semantics/openAccess ; CC BY-NC-ND 4.0 ; https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| رقم الانضمام: | edsbas.37440438 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/ofid/ofaa323 |
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