Academic Journal
Comparison of Electroencephalography in Patients With Seizures Caused by Neurosyphilis and Viral Encephalitis
| العنوان: | Comparison of Electroencephalography in Patients With Seizures Caused by Neurosyphilis and Viral Encephalitis |
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| المؤلفون: | Li-Li Zheng, Jing-Zhen Chen, Xiao-Rong Zhuang, Jia-Yin Miao |
| المصدر: | Frontiers in Neurology, Vol 13 (2022) |
| بيانات النشر: | Frontiers Media S.A. |
| سنة النشر: | 2022 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | neurosyphilis, encephalitis, viral, seizures, electroencephalography, Neurology. Diseases of the nervous system, RC346-429 |
| الوصف: | BackgroundNeurosyphilis (NS) lacks specificity in clinical and imaging features, and patients are frequently misdiagnosed as viral encephalitis when they present with seizures. This study aimed to compare electroencephalography (EEG) in patients with seizures resulting from the two diseases and provide guidance for differential diagnosis.MethodsA retrospective study on patients diagnosed with neurosyphilis and viral encephalitis with seizures in the Department of Neurology, Zhongshan Hospital, Xiamen University from 2012 to 2020.ResultsA total of 39 patients with seizures caused by neurosyphilis and 40 patients with seizures caused by viral encephalitis were included. Chi-square test analysis showed that compared with patients with viral encephalitis, patients with neurosyphilis mainly developed in middle-aged and elderly people (p < 0.001), were more likely to have temporal epileptiform discharges (p < 0.001), and less likely to have status epilepticus (SE) (p = 0.029). There was difference between two groups in the EEG performance of lateralized periodic discharges (LPDs) (p = 0.085). The two groups were matched for age and sex by case-control matching, and 25 cases in each group were successfully matched. Patients with neurosyphilis were more likely to have temporal epileptiform discharges than those with viral encephalitis (p = 0.002), and there were no significant differences in LPDs (p = 0.077) and SE (p = 0.088) between two groups.ConclusionWhen EEG shows temporal epileptiform discharges, especially in the form of LPDs, we should consider the possibility of neurosyphilis. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1664-2295 |
| Relation: | https://www.frontiersin.org/articles/10.3389/fneur.2022.879643/full; https://doaj.org/toc/1664-2295; https://doaj.org/article/ef8acdf8478c465bba9e983e2028d70f |
| DOI: | 10.3389/fneur.2022.879643 |
| الاتاحة: | https://doi.org/10.3389/fneur.2022.879643 https://doaj.org/article/ef8acdf8478c465bba9e983e2028d70f |
| رقم الانضمام: | edsbas.37140964 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 16642295 |
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| DOI: | 10.3389/fneur.2022.879643 |