Academic Journal
Transcription factors AP-2α and AP-2β regulate distinct segments of the distal nephron in the mammalian kidney
العنوان: | Transcription factors AP-2α and AP-2β regulate distinct segments of the distal nephron in the mammalian kidney |
---|---|
المؤلفون: | Joseph O. Lamontagne, Hui Zhang, Alia M. Zeid, Karin Strittmatter, Alicia D. Rocha, Trevor Williams, Sheryl Zhang, Alexander G. Marneros |
المصدر: | Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022) |
بيانات النشر: | Nature Portfolio |
سنة النشر: | 2022 |
المجموعة: | Directory of Open Access Journals: DOAJ Articles |
مصطلحات موضوعية: | Science |
الوصف: | How the distal nephron is patterned during kidney development has been difficult to study. Here they show that AP-2β is required for the formation and postnatal function of distal convoluted tubules, whereas AP-2α has a role in maintaining the structure of medullary collecting ducts. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 2041-1723 |
Relation: | https://doi.org/10.1038/s41467-022-29644-3; https://doaj.org/toc/2041-1723; https://doaj.org/article/09580c4613c64e9d94e3ad0c783bf184 |
DOI: | 10.1038/s41467-022-29644-3 |
الاتاحة: | https://doi.org/10.1038/s41467-022-29644-3 https://doaj.org/article/09580c4613c64e9d94e3ad0c783bf184 |
رقم الانضمام: | edsbas.36A934F0 |
قاعدة البيانات: | BASE |
تدمد: | 20411723 |
---|---|
DOI: | 10.1038/s41467-022-29644-3 |