التفاصيل البيبلوغرافية
| العنوان: |
Evaluation of Antiplasmodial Activity of Flavanones from Macaranga hosei Leaves |
| المؤلفون: |
Eva Marliana, Department of Chemistry, Faculty of Mathematics and Natural Sciences, Mulawarman University, Jl. Barong Tongkok 4 Samarinda 75123, East Kalimantan, Indonesia. Tel./Fax. +62-541-749140, Tjitjik Srie Tjahjandarie, Department of Chemistry, Faculty of Science and Technology, Airlangga University, Campus C Mulyorejo, Surabaya 60115, East Java, Indonesia. Tel./Fax. +62-31-5936502, Mulyadi Tanjung |
| المصدر: |
International Conference on Science, Technology, and Engineering for Sustainable Development (ICoSTES); The 1st ICoSTES 2018 |
| بيانات النشر: |
International Conference on Science, Technology, and Engineering for Sustainable Development (ICoSTES) |
| سنة النشر: |
2018 |
| الوصف: |
Macaranga hosei is one of the species of Macaranga that widely distributed in tropical forest region including Indonesia. Several compounds from the leaves of this plant with broad spectrum of biological activities have been reported. This study was focus on antiplasmodial activity of four flavanones that have been isolated, named 4´-O-methyl-8-isoprenylnaringenin (1), lonchocarpol A (2), 4´-O-methyl-8-isoprenyleriodictyol (3) and 6-isoprenyleriodictyol (4). The antiplasmodial activity against Plasmodium falciparum 3D7 was conducted using Giemsa method. The most active compound was shown by 4 with IC50 value of 0.31 μg/mL, followed by 1, 2 and 3 with IC50 values of 1.02, 1.18 and 2.47 μg/mL, respectively. Keywords: Macaranga hosei, antiplasmodial activity, flavanones, Plasmodium falciparum |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| Relation: |
https://conference.unisma.ac.id/index.php/icostes/icostes2018/paper/view/274 |
| الاتاحة: |
https://conference.unisma.ac.id/index.php/icostes/icostes2018/paper/view/274 |
| Rights: |
Authors who submit to this conference agree to the following terms: a) Authors retain copyright over their work, while allowing the conference to place this unpublished work under a Creative Commons Attribution License , which allows others to freely access, use, and share the work, with an acknowledgement of the work's authorship and its initial presentation at this conference. b) Authors are able to waive the terms of the CC license and enter into separate, additional contractual arrangements for the non-exclusive distribution and subsequent publication of this work (e.g., publish a revised version in a journal, post it to an institutional repository or publish it in a book), with an acknowledgement of its initial presentation at this conference. c) In addition, authors are encouraged to post and share their work online (e.g., in institutional repositories or on their website) at any point before and after the conference. |
| رقم الانضمام: |
edsbas.3693584F |
| قاعدة البيانات: |
BASE |