Academic Journal

Mechanism and clinical evidence of immunotherapy in allergic rhinitis

التفاصيل البيبلوغرافية
العنوان: Mechanism and clinical evidence of immunotherapy in allergic rhinitis
المؤلفون: De Carli M., Capezzali E., Tonon S., Frossi B.
المساهمون: De Carli, M., Capezzali, E., Tonon, S., Frossi, B.
سنة النشر: 2023
المجموعة: Università degli Studi di Udine: CINECA IRIS
مصطلحات موضوعية: allergic immunotherapy, allergic rhiniti, gender difference, rhinosinusiti, vaccines
الوصف: Allergic rhinitis is a common upper airway disease caused by hypersensitivity to various aeroallergens. It causes increased inflammation throughout the body and may be complicated by other otolaryngological pathologies such as chronic hyperplastic eosinophilic sinusitis, nasal polyposis, and serous otitis media. Allergic rhinitis is an IgE-mediated disease and immunotherapy can be a possible approach for patients to limit the use of antihistamines and corticosteroids. There is evidence that allergen immunotherapy can prevent the development of new sensitizations and reduce the risk of later development of asthma in patients with allergic rhinitis. However, some patients do not benefit from this approach and the efficacy of immunotherapy in reducing the severity and relapse of symptoms is still a matter of debate. This review highlights new aspects of allergic rhinitis with a particular focus on the impact of sexual dimorphism on the disease manifestation and efficacy to the allergen specific immunotherapy.
نوع الوثيقة: article in journal/newspaper
اللغة: English
Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:001049664100001; volume:4; firstpage:1217388; journal:FRONTIERS IN ALLERGY; https://hdl.handle.net/11390/1256265; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85168277519
DOI: 10.3389/falgy.2023.1217388
الاتاحة: https://hdl.handle.net/11390/1256265
https://doi.org/10.3389/falgy.2023.1217388
Rights: info:eu-repo/semantics/openAccess
رقم الانضمام: edsbas.368F27E8
قاعدة البيانات: BASE
الوصف
DOI:10.3389/falgy.2023.1217388