Towards the Standardization of the Dark/Light Transition Test with Danio rerio embryos - Preliminary Results from an Inter-laboratory Ring Test

التفاصيل البيبلوغرافية
العنوان: Towards the Standardization of the Dark/Light Transition Test with Danio rerio embryos - Preliminary Results from an Inter-laboratory Ring Test
المؤلفون: Massei, Riccardo, Christou, Maria, Schroeder, Katja, Ottermanns, Richard, Domingues, Inês, Pavlaki, Maria, Monteiro, Marta, Zwart, Edwin, Hessel, Ellen, Johann, Sarah, Knapen, Dries, Vergauwen, Lucia, Huyghe, Kato, Kjær, Pernille Ambus, Holbech, Henrik, Molina, Beatriz, Muriana, Arantza, Sebire, Marion, Lillicrap, Adam
المصدر: setac eu, SETAC Europe 34th Annual Meeting, Sevilla, 5 – 9 May 2024
بيانات النشر: Zenodo
سنة النشر: 2024
المجموعة: Zenodo
مصطلحات موضوعية: zebrafish, behaviour, ringtest, OECD, LMR
الوصف: One of the most commonly utilized behavioral assays with zebrafish embryos is the dark/light transition test (DLTT). This test involves recording and quantifying the swimming activities of zebrafish eleutheroembryos under different light conditions. The DLTT lacks standardization, and guidelines have yet to be established. As a result, zebrafish laboratories employ in-house protocols to record the activity of zebrafish eleutheroembryos. Different statistical tests are employed to explain the results and analyze the output. Consequently, comparing the results across different studies becomes a challenging task and poses a potential obstacle to bring these tests to regulators. Prior to developing a universal and standard guideline, it is necessary to characterize and understand the general variation in the DLTT.
نوع الوثيقة: conference object
اللغة: English
Relation: https://doi.org/10.5281/zenodo.12095146; https://doi.org/10.5281/zenodo.12095147; oai:zenodo.org:12095147
DOI: 10.5281/zenodo.12095147
الاتاحة: https://doi.org/10.5281/zenodo.12095147
Rights: info:eu-repo/semantics/openAccess ; Creative Commons Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/legalcode
رقم الانضمام: edsbas.34736AE
قاعدة البيانات: BASE