Academic Journal

Identification and characterization of tools used to assess penicillin allergy: structured review ; Identificación y caracterización de herramientas para evaluar la alergia a las penicilinas: Revisión estructurada

التفاصيل البيبلوغرافية
العنوان: Identification and characterization of tools used to assess penicillin allergy: structured review ; Identificación y caracterización de herramientas para evaluar la alergia a las penicilinas: Revisión estructurada
المؤلفون: Osorio-Tapiero, Liliana Marcela, Amariles, Pedro, Holguín, Hector, Salazar-Ospina, Andrea, Ortiz Rendón, Milena
المصدر: Ars Pharmaceutica (Internet); Vol. 65 No. 2 (2024); 159-177 ; Ars Pharmaceutica (Internet); Vol. 65 Núm. 2 (2024); 159-177 ; 2340-9894 ; 0004-2927
بيانات النشر: Editorial Universidad de Granada
سنة النشر: 2024
المجموعة: Portal de revistas de la Universidad de Granada
مصطلحات موضوعية: Alergia penicilinas, pruebas cutáneas, pruebas de provocación oral, antibióticos betalactámicos, Allergy penicillins, skin tests, oral challenge tests, beta-lactam antibiotics
الوصف: Introduction: Allergic reactions are one of the most serious safety problems associated with the use of medications, with allergy to beta-lactam antibiotics being the most prevalent. In fact, the American Academy of Allergy, Asthma and Immunology (AAAAI) states that penicillin allergy testing can help identify inpatients and outpatients who could safely tolerate and use this group of antibiotics and avoid labels that limit the use of beta-lactam antibiotics indefinitely. Objective: To identify the tools available in the literature to assess the history of allergy to penicillins and propose a tool that consolidates the information extracted. Methodology: Structured review on PubMed/MEDLINE between June 1, 2015 until November 30, 2022; using the search terms MeSH: (((“skin tests”[MeSH Terms]) OR (“skin irritancy tests”[MeSH Terms])) AND (“penicillins”[All Fields])) AND (“drug hypersensitivity”[MeSH Terms]). Papers in English and Spanish with access to full text and human trials, regarding available tools used to evaluate penicillin allergies were included. Results: A total of 201 articles were identified, of which after an independent evaluation, 108 were included. Among the tools to evaluate penicillin allergy, in vivo tests were identified: skin tests, oral provocation tests, patch tests and in vitro tests: specific IgE tests, determination of tryptase, histamine, T lymphocytes and basophilic activation tests. Of the patients (1181) reported with penicillin allergy, 905 (77 %) had their allergy assessed with skin testing or oral challenge tests, and only 2 % of them had a confirmed allergic reaction. Conclusion: Skin tests and oral provocation tests added to some in vivo/in vitro combinations were the most used tools to evaluate penicillin allergy. ; Introducción: Las reacciones alérgicas son uno de los problemas de seguridad más graves asociadas al uso de medicamentos, siendo la alergia a los antibióticos betalactámicos la más prevalente. Las pruebas de alergia a las penicilinas pueden ayudar a identificar ...
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: Spanish; Castilian
Relation: https://revistaseug.ugr.es/index.php/ars/article/view/29840/27242; https://revistaseug.ugr.es/index.php/ars/article/view/29840
الاتاحة: https://revistaseug.ugr.es/index.php/ars/article/view/29840
Rights: Derechos de autor 2024 Liliana Marcela Osorio-Tapiero ; https://creativecommons.org/licenses/by-nc-sa/4.0
رقم الانضمام: edsbas.343964BE
قاعدة البيانات: BASE