Academic Journal
A modified chain-based sponge dressing controls junctional hemorrhage in the tactical combat casualty care simulation of pigs
| العنوان: | A modified chain-based sponge dressing controls junctional hemorrhage in the tactical combat casualty care simulation of pigs |
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| المؤلفون: | Wu, Weihang, Liu, Wangwu, Lin, Nan, Zhao, Hu, Yang, Jin, Ye, Zhi, Yang, Weijin, Wang, Yu, Fang, Yongchao |
| المساهمون: | National Major Science and Technology Projects of China, 900TH Hospital of the Joint Logistics Support Force, The Military General Project |
| المصدر: | Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine ; volume 31, issue 1 ; ISSN 1757-7241 |
| بيانات النشر: | Springer Science and Business Media LLC |
| سنة النشر: | 2023 |
| الوصف: | Background Hemorrhage has always been the focus of battlefield and pre-hospitalization treatment. With the increasing fatality rates associated with junctional bleeding, treatment of bleeding at junctional sites has gradually gained attention in battlefield trauma emergency care. We designed a modified chain-based sponge dressing with a medical polyvinyl alcohol sponge that can be used to treat junctional hemorrhage and tested its hemostatic efficacy and biocompatibility. Methods Twenty adult Bama miniature pigs were randomly divided into the modified chain-based sponge dressing (MCSD) and standard gauze (SG) groups. The right femoral artery of the pigs was shot at after anesthesia. The Bama miniature pigs were moved to the safety zone immediately to assess the condition according to the MARCH strategy, which evaluates massive hemorrhaging, airway obstruction, respiratory status, circulatory status, head injury & hypothermia. Hemoglobin and coagulation status were checked during the experiment.Among the pigs in which the inguinal hemorrhagic model based on bullet penetrating wounds was successfully established, those in the MCSD group received a disinfected MCSD for hemostasis, while those in the SG group received standard gauze in an imbricate manner to pack the bullet exit and entrance wounds to stop bleeding until the wound was filled, followed by compression for 3 min at sufficient pressure. CT scanning, transmission electron microscopy, and HE staining were conducted after experiment. Results The MCSD group showed lower hemostasis time and blood loss than the gauze group. The MCSD group also showed a higher success rate of treatment,more stable vital signs and hemoglobin level. The CT scanning results showed tighter packing without large gaps in the MCSD group. The histopathological assessments and the transmission electron microscopy and HE staining findings indicated good biocompatibility of the polyvinyl alcohol sponge. Conclusion The MCSD met the battlefield’s requirements of speedy ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1186/s13049-023-01133-6 |
| DOI: | 10.1186/s13049-023-01133-6.pdf |
| DOI: | 10.1186/s13049-023-01133-6/fulltext.html |
| الاتاحة: | http://dx.doi.org/10.1186/s13049-023-01133-6 https://link.springer.com/content/pdf/10.1186/s13049-023-01133-6.pdf https://link.springer.com/article/10.1186/s13049-023-01133-6/fulltext.html |
| Rights: | https://creativecommons.org/licenses/by/4.0 ; https://creativecommons.org/licenses/by/4.0 |
| رقم الانضمام: | edsbas.33E6ECE5 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/s13049-023-01133-6 |
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